Epidemiological and genetic clues for molecular mechanisms involved in uterine leiomyoma development and growth

AE Commandeur, AK Styer… - Human Reproduction …, 2015 - academic.oup.com
BACKGROUND Uterine leiomyomas (fibroids) are highly prevalent benign smooth muscle
tumors of the uterus. In the USA, the lifetime risk for women developing uterine leiomyomas …

Renoprotective potentials of small molecule natural products targeting mitochondrial dysfunction

MA Rahman, S Akter, D Dorotea… - Frontiers in …, 2022 - frontiersin.org
Kidney diseases, including acute kidney injury (AKI) and chronic kidney disease (CKD),
have become critical clinical, socioeconomic, and public health concerns worldwide. The …

CD44-targeted hyaluronic acid-curcumin prodrug protects renal tubular epithelial cell survival from oxidative stress damage

JB Hu, SJ Li, XQ Kang, J Qi, JH Wu, XJ Wang… - Carbohydrate …, 2018 - Elsevier
Based on the abnormally increased expression of CD44 receptors on renal tubule epithelial
cells during ischemia/reperfusion-induced acute kidney injury (AKI), we developed a …

Enhanced Wound Healing Potential of Spirulina platensis Nanophytosomes: Metabolomic Profiling, Molecular Networking, and Modulation of HMGB-1 in an …

H Refai, AA El-Gazar, GM Ragab, DH Hassan… - Marine Drugs, 2023 - mdpi.com
Excisional wounds are considered one of the most common physical injuries. This study
aims to test the effect of a nanophytosomal formulation loaded with a dried hydroalcoholic …

Melatonin improves endoplasmic reticulum stress-mediated IRE1α pathway in Zücker diabetic fatty rat

S Aouichat, M Navarro-Alarcon, P Alarcón-Guijo… - Pharmaceuticals, 2021 - mdpi.com
Obesity and diabetes are linked to an increased prevalence of kidney disease. Endoplasmic
reticulum stress has recently gained growing importance in the pathogenesis of obesity and …

Thymoquinone ameliorates renal damage in unilateral ureteral obstruction in rats

S Hosseinian, AK Rad, AE Bideskan… - Pharmacological …, 2017 - Elsevier
Background It is well established that renin-angiotensin system (RAS) play a central role in
pathophysiology of renal damage following unilateral ureteral obstruction (UUO). The …

Corni Fructus Alleviates UUO‐Induced Renal Fibrosis via TGF‐β/Smad Signaling

JA Lee, MR Shin, SS Roh - Biomed Research International, 2022 - Wiley Online Library
Renal fibrosis is a type of chronic kidney disease (CKD) induced by infiltration of
inflammatory cells, myofibroblast accumulation, and ECM production in the kidney. From a …

Gingival fibroblasts resist apoptosis in response to oxidative stress in a model of periodontal diseases

R Cheng, D Choudhury, C Liu, S Billet, T Hu… - Cell Death …, 2015 - nature.com
Periodontal diseases are classified as inflammation affecting the supporting tissue of teeth,
which eventually leads to tooth loss. Mild reversible gingivitis and severe irreversible …

Toll-like receptors and their role in renal pathologies

T Eleftheriadis, G Pissas, V Liakopoulos… - … & Allergy-Drug …, 2012 - ingentaconnect.com
Toll-like receptors (TLRs) are the first identified and best studied family of pattern recognition
receptors. Expressed in immunocytes, TLRs initiate innate immune responses and …

[HTML][HTML] Preventive effect of fermented black ginseng against cisplatin-induced nephrotoxicity in rats

K Jung, JM An, DW Eom, KS Kang, SN Kim - Journal of Ginseng Research, 2017 - Elsevier
Background Fermented black ginseng (FBG) is processed ginseng by the repeated heat
treatment and fermentation of raw ginseng. The protective effect and mechanism of FBG on …