Nanomedicine embraces cancer radio-immunotherapy: mechanism, design, recent advances, and clinical translation

H Li, Q Luo, H Zhang, X Ma, Z Gu, Q Gong… - Chemical Society …, 2023 - pubs.rsc.org
Cancer radio-immunotherapy, integrating external/internal radiation therapy with immuno-
oncology treatments, emerges in the current management of cancer. A growing number of …

Research progress of TXNIP as a tumor suppressor gene participating in the metabolic reprogramming and oxidative stress of cancer cells in various cancers

Y Chen, J Ning, W Cao, S Wang, T Du, J Jiang… - Frontiers in …, 2020 - frontiersin.org
Thioredoxin-interacting protein (TXNIP) is a thioredoxin-binding protein that can mediate
oxidative stress, inhibit cell proliferation, and induce apoptosis by inhibiting the function of …

Engineering a HEK-293T exosome-based delivery platform for efficient tumor-targeting chemotherapy/internal irradiation combination therapy

C Wang, N Li, Y Li, S Hou, W Zhang, Z Meng… - Journal of …, 2022 - Springer
Exosomes are nanoscale monolayer membrane vesicles that are actively endogenously
secreted by mammalian cells. Currently, multifunctional exosomes with tumor-targeted …

Metal‐cyclic dinucleotide nanomodulator‐stimulated STING signaling for strengthened radioimmunotherapy of large tumor

D Wang, T Nie, C Huang, Z Chen, X Ma, W Fang… - Small, 2022 - Wiley Online Library
Combined treatment of immunotherapy and radiotherapy shows promising therapeutic
effects for the regression of a variety of cancers. However, even multi‐modality therapies …

Emerging biomaterials imaging antitumor immune response

X Ma, MJ Zhang, J Wang, T Zhang, P Xue… - Advanced …, 2022 - Wiley Online Library
Immunotherapy is one of the most promising clinical modalities for the treatment of
malignant tumors and has shown excellent therapeutic outcomes in clinical settings …

[HTML][HTML] Optical diagnostic imaging and therapy for thyroid cancer

C Shao, Z Li, C Zhang, W Zhang, R He, J Xu, Y Cai - Materials Today Bio, 2022 - Elsevier
Thyroid cancer, as one of the most common endocrine cancers, has seen a surge in
incidence in recent years. This is most likely due to the lack of specificity and accuracy of its …

State of the art in radiolabeling of antibodies with common and uncommon radiometals for preclinical and clinical immuno-PET

M Chomet, GAMS van Dongen… - Bioconjugate chemistry, 2021 - ACS Publications
Inert and stable radiolabeling of monoclonal antibodies (mAb), antibody fragments, or
antibody mimetics with radiometals is a prerequisite for immuno-PET. While radiolabeling is …

ImmunoPET: antibody-based PET imaging in solid tumors

R Manafi-Farid, B Ataeinia, S Ranjbar… - Frontiers in …, 2022 - frontiersin.org
Immuno-positron emission tomography (immunoPET) is a molecular imaging modality
combining the high sensitivity of PET with the specific targeting ability of monoclonal …

Radioiodine based biomedical carriers for cancer theranostics

J Guo, H Xiong, H Liu, T Zhang, X Sun - Coordination Chemistry Reviews, 2023 - Elsevier
Theranostics, a promising modern concept combining diagnostic capabilities and
therapeutic effects, has been used for optimizing and personalizing the treatment of many …

Development and characterization of nanobody-derived CD47 theranostic pairs in solid tumors

Y Zhang, D Zhang, S An, Q Liu, C Liang, J Li, P Liu… - Research, 2023 - spj.science.org
Overexpression of CD47 is frequently observed in various types of human malignancies,
inhibiting myeloid-mediated elimination of tumor cells and affecting the prognosis of cancer …