Q Chen, W Yan, E Duan - Nature Reviews Genetics, 2016 - nature.com
Once deemed heretical, emerging evidence now supports the notion that the inheritance of acquired characteristics can occur through ancestral exposures or experiences and that …
AJ Watkins, I Dias, H Tsuro, D Allen… - Proceedings of the …, 2018 - National Acad Sciences
The association between poor paternal diet, perturbed embryonic development, and adult offspring ill health represents a new focus for the Developmental Origins of Health and …
M Boguenet, PE Bouet, A Spiers… - Human …, 2021 - academic.oup.com
BACKGROUND The best-known role of spermatozoa is to fertilize the oocyte and to transmit the paternal genome to offspring. These highly specialized cells have a unique structure …
Reproduction is required for the survival of all mammalian species, and thousands of essential'sex'genes are conserved through evolution. Basic research helps to define these …
M Jodar, S Selvaraju, E Sendler… - Human reproduction …, 2013 - academic.oup.com
BACKGROUND Spermatozoa are highly differentiated, transcriptionally inert cells characterized by a compact nucleus with minimal cytoplasm. Nevertheless they contain a …
BACKGROUND Spermatogenesis generates a small and highly specialised type of cell that is apparently incapable of transcription and translation. For many years, this dogma was …
U Sharma - Frontiers in cell and developmental biology, 2019 - frontiersin.org
The most fundamental process for the perpetuation of a species is the transfer of information from parent to offspring. Although genomic DNA contributes to the majority of the …
N Kotaja - Fertility and sterility, 2014 - Elsevier
In mammals, male gametes are produced inside the testis by spermatogenesis, which has three phases: mitotic proliferation of spermatogonia, meiosis of spermatocytes, and haploid …
Even though the genetic fingerprint of human sperm has been defined, its role in orchestrating fertilization and the development of the early embryo remains vague. Here we …