Polygenic adaptation: a unifying framework to understand positive selection

N Barghi, J Hermisson, C Schlötterer - Nature Reviews Genetics, 2020 - nature.com
Most adaption processes have a polygenic genetic basis, but even with the recent explosive
growth of genomic data we are still lacking a unified framework describing the dynamics of …

275 years of forestry meets genomics in Pinus sylvestris

T Pyhäjärvi, ST Kujala… - Evolutionary Applications, 2020 - Wiley Online Library
Pinus sylvestris has a long history of basic and applied research that is relevant for both
forestry and evolutionary studies. Its patterns of adaptive variation and role in forest …

Polygenic adaptation: From sweeps to subtle frequency shifts

I Höllinger, PS Pennings, J Hermisson - PLoS genetics, 2019 - journals.plos.org
Evolutionary theory has produced two conflicting paradigms for the adaptation of a
polygenic trait. While population genetics views adaptation as a sequence of selective …

Global adaptation complicates the interpretation of genome scans for local adaptation

TR Booker, S Yeaman, MC Whitlock - Evolution Letters, 2021 - academic.oup.com
Spatially varying selection promotes variance in allele frequencies, increasing genetic
differentiation between the demes of a metapopulation. For that reason, outliers in the …

Population genetic models for the spatial spread of adaptive variants: A review in light of SARS-CoV-2 evolution

MC Steiner, J Novembre - PLoS Genetics, 2022 - journals.plos.org
Theoretical population genetics has long studied the arrival and geographic spread of
adaptive variants through the analysis of mathematical models of dispersal and natural …

The impact of long-range dispersal on gene surfing

J Paulose, O Hallatschek - Proceedings of the National …, 2020 - National Acad Sciences
Range expansions lead to distinctive patterns of genetic variation in populations, even in the
absence of selection. These patterns and their genetic consequences have been well …

Population genomics perspectives on convergent adaptation

KM Lee, G Coop - … Transactions of the Royal Society B, 2019 - royalsocietypublishing.org
Convergent adaptation is the independent evolution of similar traits conferring a fitness
advantage in two or more lineages. Cases of convergent adaptation inform our ideas about …

A theory of oligogenic adaptation of a quantitative trait

I Höllinger, B Wölfl, J Hermisson - Genetics, 2023 - academic.oup.com
Rapid phenotypic adaptation is widespread in nature, but the underlying genetic dynamics
remain controversial. Whereas population genetics envisages sequential beneficial …

Evolutionary dynamics in structured populations under strong population genetic forces

AF Feder, PS Pennings, J Hermisson… - G3: Genes, Genomes …, 2019 - academic.oup.com
In the long-term neutral equilibrium, high rates of migration between subpopulations result in
little population differentiation. However, in the short-term, even very abundant migration …

Population genetics meets ecology: a guide to individual-based simulations in continuous landscapes

ET Chevy, J Min, V Caudill, SE Champer, BC Haller… - …, 2024 - pmc.ncbi.nlm.nih.gov
Individual-based simulation has become an increasingly crucial tool for many fields of
population biology. However, implementing realistic and stable simulations in continuous …