Cell therapies represent a rapidly emerging class of new therapeutics. They are intended
and developed for the treatment of some of the most prevalent human diseases, including …

Induced pluripotent stem cells (iPSCs) have entered an unprecedented state of
development since they were first generated. They have played a critical role in disease …

Chimeric antigen receptor T cell therapy (CAR-T) has been rolled out as a new treatment for
hematological malignancies. For solid tumor treatment, CAR-T has been disappointing so …

The current organoid culture systems allow pluripotent and adult stem cells to self-organize
to form three-dimensional (3D) structures that provide a faithful recapitulation of the …

Immunotherapy is a relatively new treatment regimen for cancer, and it is based on the
modulation of the immune system to battle cancer. Immunotherapies can be classified as …

Background Metastasis is a hallmark of cancer and responsible for most cancer deaths.
Migrastatics were defined as drugs interfering with all modes of cancer cell invasion and …

Regulatory T cells (Tregs) are emerging as a new cell-based therapy in solid organ
transplantation. Adoptive transfer of Tregs has been shown preclinically to protect from graft …

Cell-based therapies have been making great advances toward clinical reality. Despite the
increase in trial activity, few therapies have successfully navigated late-phase clinical trials …

Tissue engineering strategies, notably biomaterials, can be modularly designed and tuned
to match specific patient needs. While many challenges within tissue engineering remain …

Several types of gene-and cell-based therapeutics are now emerging in the cancer
immunotherapy, transplantation, and regenerative medicine landscapes. Radionuclear …