Synthesis, in vitro α-glucosidase inhibitory potential and in silico study of 2‑chloro pyridine incorporated thiosemicarbazones

AR Pasha, S Ullah, A Khan, M al-Rashida… - Journal of Molecular …, 2024 - Elsevier
Diabetes is a devastating metabolic illness that affects people of all ages and is widespread
around the world as a result of the malfunctioning of prior treatment approaches. This work …

Biomolecular Interactions and Anticancer Mechanisms of Ru (II)-Arene Complexes of Cinnamaldehyde-Derived Thiosemicarbazone Ligands: Analysis Combining In …

VN Vadakkedathu Palakkeezhillam… - ACS Applied Bio …, 2024 - ACS Publications
Our study focuses on synthesizing and exploring the potential of three N-(4) substituted
thiosemicarbazones derived from cinnamic aldehyde, alongside their Ru (II)-(η6-p …

Bioactive O^ N^ O^ Schiff base appended homoleptic titanium (iv) complexes: DFT, BSA/CT-DNA interactions, molecular docking and antitumor activity against HeLa …

S Thanigachalam, M Pathak - RSC advances, 2024 - pubs.rsc.org
Five new homoleptic derivatives of titanium (IV) have been developed and characterized by
physicochemical techniques. Metal complexes, TiH2L1 [(C38H26N6O4) Ti], TiH2L2 …

In vitro cytotoxic study of synthesized Ag and Ce dual-doped α-Fe2O3 nanoparticles on NIH/3T3 and U87 cell lines

M Sarani, M Barani, S Darijani, M Adeli-Sardou… - Inorganic Chemistry …, 2024 - Elsevier
The significant potential of iron oxide nanoparticles in biomedical fields, particularly in the
delivery of anticancer drugs and in sono-chemodynamic therapy, can be attributed to their …

Two New Inner-sphere Pt (II) Thiosemicarbazone Schiff Base Complexes Immobilized into Magnetic Nanoparticles: Synthesis, Characterization, and Biological …

AWA El-Ata, MM El-Gamil, YG Abou El-Reash… - Inorganic Chemistry …, 2024 - Elsevier
This study explores the synthesis, characterization, and biological investigations of two new
Pt (II) thiosemicarbazone complexes immobilized in magnetic nanoparticles (MNPs). MNPs …

Mitochondria-targeted ruthenium complexes can be generated in vitro and in living cells to target triple-negative breast cancer cells by autophagy inhibition

GD Zhang, MM Wang, Y Su, H Fang, XL Xue… - Journal of Inorganic …, 2024 - Elsevier
Triple-negative breast cancer (TNBC) is the most aggressive type of breast cancer, which
owned severe resistance to platinum-based anticancer agents. Herein, we report a new …

[HTML][HTML] Group VA Aromatic Thiosemicarbazone Complexes: Synthesis, Characterization, Biological Activity, and Topological Studies

II Ozturk, EI Sumer, G Dutkiewicz, CN Banti… - International Journal of …, 2024 - mdpi.com
The antiproliferative and antibacterial activities of thiosemicarbazones increase markedly
with the presence of metal ions. One of the factors determining the activity of metal …

In Vitro and In Vivo Biological Evaluation of Novel 1,4‐Naphthoquinone Derivatives as Potential Anticancer Agents

P Ravichandiran, A Martyna, E Kochanowicz… - …, 2024 - Wiley Online Library
A novel library of naphthoquinone derivatives (3–5 aa) was synthesized and evaluated for
their anticancer properties. Specifically, compounds 5 i, 5 l, 5 o, 5 q, 5 r, 5 s, 5 t, and 5 v …

Investigation of the anticancer, antibacterial, and anti-inflammatory activity of (R)-(−)-carvone and (S)-(+)-carvone essential oils on Ag13, Ag13-, and Ag13+ silver …

R Zainul, IS Gataa, ZY Abdullah, R Roopashree… - Inorganic Chemistry …, 2024 - Elsevier
New chemical drugs have challenges like adverse side effects and drug release. Essential
oils have applications in drug production but face limitations like solubility and instability. On …