Traditionally, platelets are known to play an important role in haemostasis and thrombosis;
however, they serve also as important modulators of inflammation and immunity. Platelets …

Antiplatelet drugs serve as a first-line antithrombotic therapy for the management of acute
ischemic events and the prevention of secondary complications in vascular diseases …

Platelet activation is relevant to a variety of acute thrombotic events. We sought to examine
adenosine 5′-monophosphate (AMP) mechanisms of action in preventing platelet …

Salviae miltiorrhiza (Danshen) has been used for thousands of years in China and some
other Asian countries to treat atherothrombotic diseases. Salvianolate which consists of …

Aberrant platelet activation plays a critical role in the pathogenesis of heart attack and
stroke. dl-3-n-butylphthalide (NBP) has been approved in China to treat stroke with multiple …

Several adenosine receptor (AR) agonists have been shown in the past to possess anti-
platelet potential; however, the adjunctive role of AR agonists in anti-platelet therapy with the …

A series of adenosine and 2′-deoxyadenosine pairs modified with a 1, 12-dicarba-closo-
dodecaborane cluster or alternatively with a phenyl group at the same position was …

Aim: Psm2, one of the pyrrolidinoindoline alkaloids isolated from whole Selaginella
moellendorffii plants, has shown a potent antiplatelet activity. In this study, we further …

Summary Background 5, 6‐Dimethylxanthenone‐4‐acetic acid (DMXAA) is a tumor vascular
disrupting agent under clinical trials as an adjacent antitumor agent. DMXAA is structurally …

Blood platelets' adenosine receptors (AR) are considered to be a new target for the anti-
platelet therapy. This idea is based on in vitro studies which show that signaling mediated by …