The hand endows us with unparalleled precision and versatility in our interactions with
objects, from mundane activities such as grasping to extraordinary ones such as virtuoso …

Skilled motor behaviour, from the graceful leap of a ballerina to a precise pitch by a baseball
player, appears effortless but reflects an intimate interaction between the complex …

Humans possess an extraordinary capacity for cultural production, from the arts and
language to science and technology. How did the human mind—and the uniquely human …

In most animals, the brain controls the body via a set of descending neurons (DNs) that
traverse the neck. DN activity activates, maintains or modulates locomotion and other …

In the neocortex, subcerebral axonal projections originate largely from layer 5 (L5)
extratelencephalic-projecting (ET) neurons. The unique morpho-electric properties of these …

What changes in neural architecture account for the emergence and expansion of dexterity
in primates? Dexterity, or skill in performing motor tasks, depends on the ability to generate …

This book presents a comprehensive account of the regions of the brain that control the
performance of skilled voluntary movements, especially the accurate and precise control of …

An appreciation of the comparative functions of the corticospinal tract is of direct relevance to
the understanding of how results from animal models can advance knowledge of the human …

Progress continues in the development of reparative interventions to enhance recovery after
experimental spinal cord injury (SCI). Here we discuss to what extent rodent models of SCI …

Tackling the question of whether control of human gait is based on that of a quadrupedal
locomotion system is of basic and practical relevance. During evolution, the increased …