Redox-and non-redox-metal-induced formation of free radicals and their role in human disease
Transition metal ions are key elements of various biological processes ranging from oxygen
formation to hypoxia sensing, and therefore, their homeostasis is maintained within strict …
formation to hypoxia sensing, and therefore, their homeostasis is maintained within strict …
The important role of zinc in neurological diseases
Zinc is one of the most abundant metal ions in the central nervous system (CNS), where it
plays a crucial role in both physiological and pathological brain functions. Zinc promotes …
plays a crucial role in both physiological and pathological brain functions. Zinc promotes …
Zinc and human health: an update
CT Chasapis, AC Loutsidou, CA Spiliopoulou… - Archives of …, 2012 - Springer
The importance of micronutrients in health and nutrition is undisputable, and among them,
zinc is an essential element whose significance to health is increasingly appreciated and …
zinc is an essential element whose significance to health is increasingly appreciated and …
Tumor microenvironment-triggered intratumoral in-situ biosynthesis of inorganic nanomaterials for precise tumor diagnostics
X Zhang, Q Zhao, J Yang, T Wang, F Chen… - Coordination Chemistry …, 2023 - Elsevier
The severe side effects and low bioavailability of conventional chemotherapeutic drugs are
the major problems that current clinical cancer treatments suffer from. In recent years, tumor …
the major problems that current clinical cancer treatments suffer from. In recent years, tumor …
Mechanistic explanations how cell-mediated immune activation, inflammation and oxidative and nitrosative stress pathways and their sequels and concomitants play a …
B Leonard, M Maes - Neuroscience & Biobehavioral Reviews, 2012 - Elsevier
This paper reviews that cell-mediated-immune (CMI) activation and inflammation contribute
to depressive symptoms, including anhedonia; anxiety-like behaviors; fatigue and somatic …
to depressive symptoms, including anhedonia; anxiety-like behaviors; fatigue and somatic …
Zinc and the modulation of redox homeostasis
PI Oteiza - Free Radical Biology and Medicine, 2012 - Elsevier
Zinc, a redox-inactive metal, has been long viewed as a component of the antioxidant
network, and growing evidence points to its involvement in redox-regulated signaling. These …
network, and growing evidence points to its involvement in redox-regulated signaling. These …
Zinc in the brain: friend or foe?
Zinc is a trace metal ion in the central nervous system that plays important biological roles,
such as in catalysis, structure, and regulation. It contributes to antioxidant function and the …
such as in catalysis, structure, and regulation. It contributes to antioxidant function and the …
Metal-organic framework materials promote neural differentiation of dental pulp stem cells in spinal cord injury
Spinal cord injury (SCI) is accompanied by loss of Zn2+, which is an important cause of
glutamate excitotoxicity and death of local neurons as well as transplanted stem cells …
glutamate excitotoxicity and death of local neurons as well as transplanted stem cells …
Role of the blood–brain barrier in the nutrition of the central nervous system
P Campos-Bedolla, FR Walter, S Veszelka… - Archives of medical …, 2014 - Elsevier
The blood–brain barrier (BBB) is a dynamic and complex interface between the blood and
the central nervous system regulating brain homeostasis. Major functions of the BBB include …
the central nervous system regulating brain homeostasis. Major functions of the BBB include …
Zinc in the central nervous system: From molecules to behavior
SD Gower‐Winter, CW Levenson - Biofactors, 2012 - Wiley Online Library
The trace metal zinc is a biofactor that plays essential roles in the central nervous system
across the lifespan from early neonatal brain development through the maintenance of brain …
across the lifespan from early neonatal brain development through the maintenance of brain …