[HTML][HTML] Investigating the cationic side chains of the antimicrobial peptide tritrpticin: hydrogen bonding properties govern its membrane-disruptive activities

LT Nguyen, L de Boer, SAJ Zaat, HJ Vogel - Biochimica et Biophysica Acta …, 2011 - Elsevier
The positively charged side chains of cationic antimicrobial peptides are generally thought
to provide the initial long-range electrostatic attractive forces that guide them towards the …

Elucidation of the mechanism of single-stranded DNA interaction with methylene blue: A spectroscopic approach

M Ortiz, A Fragoso, PJ Ortiz, CK O'Sullivan - Journal of Photochemistry and …, 2011 - Elsevier
The interaction of photosensitizer methylene blue (MB) with single stranded
oligonucleotides of composition AAA-AAA-AAA (A9), CCC-CCC-CCC (C9), GGG-GGG-GGG …

[HTML][HTML] Hydroxy-tryptophan containing derivatives of tritrpticin: Modification of antimicrobial activity and membrane interactions

M Arias, KV Jensen, LT Nguyen, DG Storey… - Biochimica Et Biophysica …, 2015 - Elsevier
Tritrpticin is an antimicrobial peptide with a strong microbicidal activity against Gram-positive
and Gram-negative bacteria as well as fungi. The 13-residue peptide is essentially …

Fluorescence and absorbance spectroscopy methods to study membrane perturbations by antimicrobial host defense peptides

M Arias, HJ Vogel - Antimicrobial Peptides: Methods and Protocols, 2017 - Springer
Antimicrobial peptides (AMPs) are currently intensely studied because of their potential as
new bactericidal and bacteriostatic agents. The mechanism of action of numerous AMPs …

Jack bean α-mannosidase (Jbα-man): Tolerance to alkali, chelating and reducing agents and energetics of catalysis and inhibition

A Kumar, SM Gaikwad - International journal of biological macromolecules, 2011 - Elsevier
Investigations of the catalytic and structural transitions of jack bean α-mannosidase (Jbα-
man) are described in the present paper. The enzyme was maximally stable at pH 5.0; …

Class II α-mannosidase from Aspergillus fischeri: energetics of catalysis and inhibition

KS Shashidhara, SM Gaikwad - International Journal of Biological …, 2009 - Elsevier
Energetics of the catalysis of Class II α-mannosidase (EC 3.2. 1.24) from Aspergillus fischeri
was studied. The enzyme showed Kcat/Km for Man (α1-3) Man, Man (α1-2) Man and Man …

Conformational and Functional Transitions in Class II α-mannosidase from Aspergillus fischeri

KS Shashidhara, SM Gaikwad - Journal of fluorescence, 2010 - Springer
The conformational transitions in an oligomeric and high molecular weight class II α-
mannosidase from Aspergillus fischeri were examined using fluorescence and CD …

Role of tryptophan in the active site of plant esterase: chemical modification and fluorometric studies

L Yang, D Huo, K He, S Zhang, C Hou - Applied biochemistry and …, 2013 - Springer
Plant esterase extracted from wheat flour play key roles in the spectrophotometric detection
of organophosphorus compounds (OPs) for food safety and human health. The purpose of …

[PDF][PDF] Interaction of a-mannosidase from aspergillus fischeri with glycosidase inhibitors, metal ions and group specific reagents

K Shashidhara, S Gaikwad, M Khan… - Res J …, 2009 - researchgate.net
As an initial step towards using omannosidase as a target against anticancer drugs,
inhibition studies of a model enzyme, class II ozmannosida se from Aspergillus fischeri in …

[PDF][PDF] Understanding the Mechanism of Action of Tryptophan-and Arginine-rich Host-Defence Peptides

M Arias - 2015 - prism.ucalgary.ca
In multicellular organisms antimicrobial peptides (AMPs) are a key component of the host
innate immune system, hence they are also known as host defence peptides. AMPs …