The upsurge of multiple drug resistance (MDR) bacteria substantially diminishes the
effectiveness of antibiotic arsenal and therefore intensifies the rate of therapeutic failure. The …

The recent pandemic of coronavirus disease 2019 (COVID-19) caused by SARS-CoV-2 has
raised global health concerns. The viral 3-chymotrypsin-like cysteine protease (3CL pro) …

The H+-coupled vesicular monoamine transporter (VMAT) is a transporter essential for life.
VMAT mediates packaging of the monoamines serotonin, dopamine, norepinephrine, and …

Large-scale metabolomics is a powerful technique that has attracted widespread attention in
biomedical studies focused on identifying biomarkers and interpreting the mechanisms of …

Objectives T-705, also known as favipiravir, is a small-molecule inhibitor that is currently in
clinical development for the treatment of influenza virus infections. This molecule also …

Introduction to Proteins provides a comprehensive and state-of-the-art introduction to the
structure, function, and motion of proteins for students, faculty, and researchers at all levels …

Oropouche virus (OROV) is an emerging pathogen which causes Oropouche fever and
meningitis in humans. Several outbreaks of OROV in South America, especially in Brazil …

The tumour suppressor p53 is the most frequently mutated gene in human cancer.
Reactivation of mutant p53 by small molecules is an exciting potential cancer therapy …

Vascular wilt of tomato caused by Fusarium oxysporum f. sp. lycopersici (FOL) is one of the
most devastating diseases, that delimits the tomato production worldwide. Fungal short …

Purpose Brain monoamine vesicular transport disease is an infantile-onset movement
disorder that mimics cerebral palsy. In 2013, the homozygous SLC18A2 variant, p …