Glucosamine is widely used to relieve symptoms from osteoarthritis. Its safety and effects on
glucose metabolism are critically evaluated in this review. The LD50 of oral glucosamine in …

Abstract Symptomatic Slow Acting Drugs for Osteoarthritis (SYSADOA), such as hyaluronic
acid (HA), chondroitin sulfate (CS) and glucosamine (GlcN) are natural compounds …

Herbs and Natural Supplements, 4th Edition: An evidence-based guide is an authoritative,
evidence-based reference. This two-volume resource is essential to the safe and effective …

Dendrimers are hyperbranched macromolecules that can be chemically synthesized to have
precise structural characteristics. We used anionic, polyamidoamine, generation 3.5 …

OBJECTIVE: Pharmacokinetic data on glucosamine are scant, limiting the understanding of
glucosamine sulfate mechanism of action in support of its treatment effects in osteoarthritis …

The prevalence of primary or idiopathic osteoarthritis (OA) of knee and hip joints has
substantially increased in general population during the last decades. Analgesics and non …

OBJECTIVE: We investigated the synovial and plasma glucosamine concentrations in
osteoarthritic patients following oral administration of crystalline glucosamine sulphate at the …

Objective To examine the concentration of glucosamine in the synovial fluid and its
pharmacokinetics in serum in a large animal model following dosing with glucosamine HCl …

Glucosamine (GlcN) is a widely utilized dietary supplement that is used to promote joint
health. Reports that oral GlcN supplementation at usual doses adversely affects glucose …

Objective To investigate how changes in the gastrointestinal tract (GIT) microbiota profile
may influence nutraceutical efficacy in osteoarthritis (OA) and allow the formulation of a …