Fungal infections are a major contributor to infectious disease-related deaths across the
globe. Candida species are among the most common causes of invasive mycotic disease …

Cryptococcus spp., in particular Cryptococcus neoformans and Cryptococcus gattii, have an
enormous impact on human health worldwide. The global burden of cryptococcal meningitis …

Protein–protein interactions (PPIs) govern all biological processes. Some small molecules
modulate PPIs through induced protein proximity. In particular, molecular glue degraders …

The fungal kingdom includes at least 6 million eukaryotic species and is remarkable with
respect to its profound impact on global health, biodiversity, ecology, agriculture …

Candidiasis is an infection caused by fungi from a Candida species, most commonly
Candida albicans. C. albicans is an opportunistic fungal pathogen typically residing on …

Our current efforts are aimed to synthesize 16 complexes of Co (II), Ni (II), Cu (II), and Zn (II)
metal ions from heterocyclic hydrazone ligands by condensation reaction of 2, 6 …

Protein phosphorylation is one of the most widely observed and important post-translational
modification (PTM) processes. Protein phosphorylation is regulated by protein kinases, each …

Fungal pathogens are a severe public health problem. The leading causative agents of
systemic fungal infections include species from the Candida, Cryptococcus, and Aspergillus …

Human fungal pathogens are the causative agents of devastating diseases across the
globe, and the increasing prevalence of drug resistance threatens to undermine the already …

Molecular Glues, here defined as small molecules that interact with two protein surfaces to
induce or enhance affinity of these two proteins to each other, have received substantial …