Our understanding of vertebrate origins is powerfully informed by comparative morphology,
embryology and genomics of chordates, hemichordates and echinoderms, which together …

The foundation of the diverse metazoan nervous systems is laid by embryonic patterning
mechanisms, involving the generation and movement of neural progenitors and their …

Increasing evidence in the last years indicates that the vast amount of regulatory information
contained in mammalian genomes is organized in precise 3D chromatin structures …

The goal of comparative developmental biology is identifying mechanistic differences in
embryonic development between different taxa and how these evolutionary changes have …

Apical organs are relatively simple larval nervous systems. The extent to which apical
organs are evolutionarily related to the more complex nervous systems of other animals …

The origin of the bilaterian head is a fundamental question for the evolution of animal body
plans. The head of bilaterians develops at the anterior end of their primary body axis and is …

Patterning the neuroectoderm along the anterior–posterior (AP) axis is a critical event in the
early development of deuterostome embryos. However, the mechanisms that regulate the …

Cell types are the building blocks of metazoan biodiversity and offer a powerful perspective
for inferring evolutionary phenomena. With the development of single-cell transcriptomic …

Wnt signalling plays an eminent role in development, stem cell growth, and tissue
homeostasis. Much of what we know about Wnt signalling, we owe to research in …

A single origin to the diverse mechanisms of metazoan neurogenesis is suggested by the
involvement of common signaling components and similar classes of transcription factors …