In last two decades, the lipid nanocarriers have been extensively investigated for their drug
targeting efficiency towards the critical areas of the human body like CNS, cardiac region …

Increased use of nanoscale particles have benefited many industries, including medicine,
electronics, and environmental cleaning. These particles provide higher material …

ABSTRACT Preclinical Research Doxorubicin (DOX) is commonly used for the treatment of
breast cancer and lymphoma. However, its clinical use has been severely limited due to …

Intranasal nanostructured lipid carrier (NLC) of lurasidone hydrochloride (LRD) for brain
delivery was prepared by the solvent evaporation method. The effects of independent …

Background: The convoluted pathophysiology of brain disorders along with penetration
issue of drugs to brain represents major hurdle that requires some novel therapies. The …

Despite significant advances in developing drugs to treat brain tumours, achieving
therapeutic concentrations of the drug at the tumour site remains a major challenge due to …

In the current study, a composite in-situ gel formulation containing aripiprazole (APZ) loaded
transfersomes (TFS) was developed for the intranasal brain targeting of APZ. APZ loaded …

In recent years, metabolic disorder, especially fatty liver disease, has been considered a
major challenge to global health. The attention of researchers focused on expanding …

Numerous studies are focused on nanoparticle penetration into the brain functionalizing
them with ligands useful to cross the blood–brain barrier. However, cell targeting is also …

Background Perphenazine (PPZ) is a typical antipsychotic that is mainly administrated for
the treatment of schizophrenia. Due to its highly lipophilic nature and extensive hepatic first …