[HTML][HTML] An overview of mammalian p38 mitogen-activated protein kinases, central regulators of cell stress and receptor signaling

J Han, J Wu, J Silke - F1000Research, 2020 - ncbi.nlm.nih.gov
The p38 family is a highly evolutionarily conserved group of mitogen-activated protein
kinases (MAPKs) that is involved in and helps co-ordinate cellular responses to nearly all …

Mapping the Protein Kinome: Current Strategy and Future Direction

Z Hou, H Liu - Cells, 2023 - mdpi.com
The kinome includes over 500 different protein kinases, which form an integrated kinase
network that regulates cellular phosphorylation signals. The kinome plays a central role in …

Fluoroquinolones suppress TGF-β and PMA-induced MMP-9 production in cancer cells: implications in repurposing quinolone antibiotics for cancer treatment

CY Huang, JL Yang, JJ Chen, SB Tai, YH Yeh… - International journal of …, 2021 - mdpi.com
Background: Fluoroquinolones (FQs) are potent antimicrobials with multiple effects on host
cells and tissues. Although FQs can attenuate cancer invasion and metastasis, the …

Exploring Specific P38α Activation and Its Effect on Lung Physiology and Pathology

MHC Kiat - 2022 - search.proquest.com
The MAP kinase p38 is expressed ubiquitously throughout all tissues, and its activity is
associated with numerous physiological processes such as cell cycle regulation …

Inhibition of dedifferentiation in primary mouse hepatocytes in vitro to generate a functional hepatic study model

B Laborit Labrada - 2021 - library-archives.canada.ca
Obesity and its related pathologies insulin resistance, type 2 Diabetes and non-alcoholic
fatty liver disease are becoming one of the major health hazards of modern world. The liver …