Oligodendrocytes generate multiple layers of myelin membrane around axons of the central
nervous system to enable fast and efficient nerve conduction. Until recently, saltatory nerve …

Oligodendrocyte precursor cells (OPCs) are a population of tissue-resident glial cells found
throughout the CNS, constituting approximately 5% of all CNS cells and persisting from …

Oligodendrocytes are the myelinating cells of the central nervous system (CNS) that are
generated from oligodendrocyte progenitor cells (OPC). OPC are distributed throughout the …

Oligodendrocyte precursor cells (OPCs) are abundant in the adult central nervous system,
and have the capacity to regenerate oligodendrocytes and myelin. However, in inflammatory …

Myelinated nerve fibers have evolved to enable fast and efficient transduction of electrical
signals in the nervous system. To act as an electric insulator, the myelin sheath is formed as …

Myelination of axons in the nervous system of vertebrates enables fast, saltatory impulse
propagation, one of the best-understood concepts in neurophysiology. However, it took a …

Recent reports have revealed that oligodendrocyte precursor cells (OPCs) are
heterogeneous. It remains unclear whether such heterogeneity reflects different subtypes of …

The adult CNS contains an abundant population of oligodendrocyte precursor cells (NG2+
cells) that generate oligodendrocytes and repair myelin, but how these ubiquitous …

Multiple sclerosis is characterized by inflammatory activity that results in destruction of the
myelin sheaths that enwrap axons. The currently available medications for multiple sclerosis …

Myelin degeneration occurs in neurodegenerative diseases and aging. In these conditions,
resident oligodendrocyte progenitor cells (OPCs) differentiate into oligodendrocytes that …