CHD7 is a member of the chromodomain helicase DNA‐binding (CHD) protein family that
plays a role in transcription regulation by chromatin remodeling. Loss‐of‐function mutations …

CHARGE syndrome is a multiple congenital anomaly condition caused, in a majority of
individuals, by loss of function pathogenic variants in the gene CHD7. In this special issue of …

De novo mutations in CHD8 are strongly associated with autism spectrum disorder, but the
basic biology of CHD8 remains poorly understood. Here we report that Chd8 knockdown …

In honeybee societies, distinct caste phenotypes are created from the same genotype,
suggesting a role for epigenetics in deriving these behaviorally different phenotypes. We …

Neural crest cells are highly migratory pluripotent cells that give rise to diverse derivatives
including cartilage, bone, smooth muscle, pigment, and endocrine cells as well as neurons …

Chromatin remodeling accompanies differentiation, however, its role in self-renewal is less
well understood. We report that in Drosophila, the chromatin remodeler Kismet/CHD7/CHD8 …

In an initial preliminary screen we identified factors associated with controlling Drosophila
aging by examining longevity in adults where EP elements induced over-expression or …

The mechanisms underlying the evolution of morphological novelties have remained
enigmatic but co-option of existing gene regulatory networks (GRNs), recruitment of genes …

Abstract Purpose of Review Individuals with autism spectrum disorders (ASD) commonly
also suffer from gastrointestinal (GI) dysfunction; however, few animal model studies have …

The Drosophila neuromuscular junction (NMJ) is a glutamatergic synapse that is structurally
and functionally similar to mammalian glutamatergic synapses. These synapses can, as a …