Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated
guidelines for the definition and interpretation of cell death from morphological, biochemical …

Type I programmed cell death (PCD) or apoptosis is critical for cellular self-destruction for a
variety of processes such as development or the prevention of oncogenic transformation …

Spermidine is a natural polyamine that stimulates cytoprotective macroautophagy/
autophagy. External supplementation of spermidine extends lifespan and health span …

Elucidating the biology of yeast in its full complexity has major implications for science,
medicine and industry. One of the most critical processes determining yeast life and …

A cell's decision to die is controlled by a sophisticated network whose deregulation
contributes to the pathogenesis of multiple diseases including neoplastic and …

Background and Objective: Stroke is a leading cause of morbidity and mortality in both
developed and developing countries all over the world. The only drug for ischemic stroke …

Mutations and deletions in the mitochondrial genome (mtDNA), as well as instability of the
nuclear genome, are involved in multiple human diseases. Here, we report that in …

Apoptosis is associated in many cases with the generation of reactive oxygen species (ROS)
in cells across a wide range of organisms including lower eukaryotes such as the yeast …

Acetic acid stress represents a frequent challenge to counteract for yeast cells under several
environmental conditions and industrial bioprocesses. The molecular mechanisms …

Unicellular, planktonic, prokaryotic and eukaryotic photoautotrophs (phytoplankton) have an
ancient evolutionary history on Earth during which time they have played key roles in the …