Hepatitis B and C viruses are a global health problem causing acute and chronic infections
that can lead to liver cirrhosis and hepatocellular carcinoma (HCC). These infections are the …

Approximately 12% of all human cancers are caused by oncoviruses. Human viral
oncogenesis is complex, and only a small percentage of the infected individuals develop …

Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer, which in
turns accounts for the sixth most common cancer worldwide. Despite being the 6 th most …

Hepatitis C infection causes a state of chronic oxidative stress, which may contribute to
fibrosis and carcinogenesis in the liver. Previous studies have shown that expression of the …

Hepatocellular carcinoma (HCC) is one of the major cancers in the world. There is a striking
variation in HCC incidence rates between various countries, with a highest‐to‐lowest ratio of …

Hepatitis C virus (HCV) infects over 170 million people worldwide. Chronic infection occurs
in 50–80% of cases and eventually leads to cirrhosis and hepatocellular carcinoma. The …

Although not frequently, hepatocellular carcinoma (HCC) can ensue in a non-cirrhotic liver.
As compared to cirrhotic HCC, this kind of tumour has some peculiarities, such as:(a) a lower …

Background & Aims: The mechanisms by which hepatitis C virus (HCV) induces liver fibrosis
are unknown. Hepatocytes secrete HCV proteins, which may interact with hepatic stellate …

Gaining knowledge on the metabolism of a drug, the enzymes involved and its inhibition or
induction potential is a necessary step in pharmaceutical development of new compounds …

Antiviral immunity requires recognition of viral pathogens and activation of cytotoxic and Th
cells by innate immune cells. In this study, we demonstrate that hepatitis C virus (HCV) core …