Generation of neuronal diversity is a biological strategy widely used in the brain to process
complex information. The olfactory bulb is the first relay station of olfactory information in the …

Smelling monomolecular odors hardly ever occurs in everyday life, and the daily functioning
of the sense of smell relies primarily on the processing of complex mixtures of volatiles that …

In a departure from previous top-down or bottom-up strategies used to understand neuronal
circuits, many forward-looking research programs now place the circuit itself at their centre …

In odorant-rich environments, animals must be able to detect specific odorants of interest
against variable backgrounds. However, studies have found that both humans and rodents …

Odor landscapes contain complex blends of molecules that each activate unique,
overlapping populations of olfactory sensory neurons (OSNs). Despite the presence of …

Sensory information is selectively or non-selectively enhanced and inhibited in the brain, but
it remains unclear whether and how this occurs at the most peripheral level. Using in vivo …

Inhibition is fundamental to information processing by neural circuits. In the olfactory bulb
(OB), glomeruli are the functional units for odor information coding, but inhibition among …

Natural environments feature mixtures of odorants of diverse quantities, qualities and
complexities. Olfactory receptor neurons (ORNs) are the first layer in the sensory pathway …

Associative fear learning produces fear toward the conditioned stimulus (CS) and often
generalization, the expansion of fear from the CS to similar, unlearned stimuli. However …

In nature, animals normally perceive sensory information on top of backgrounds. Thus, the
neural substrate to perceive under background conditions is inherent in all sensory systems …