Phosphate transport in epithelial and nonepithelial tissue
N Hernando, K Gagnon, E Lederer - Physiological reviews, 2021 - journals.physiology.org
Phosphate is an essential nutrient for life and is a critical component of bone formation, a
major signaling molecule, and structural component of cell walls. Phosphate is also a …
major signaling molecule, and structural component of cell walls. Phosphate is also a …
Deep sequencing reveals stepwise mutation acquisition in paroxysmal nocturnal hemoglobinuria
W Shen, MJ Clemente, N Hosono… - The Journal of …, 2014 - Am Soc Clin Investig
Paroxysmal nocturnal hemoglobinuria (PNH) is a nonmalignant clonal disease of
hematopoietic stem cells that is associated with hemolysis, marrow failure, and …
hematopoietic stem cells that is associated with hemolysis, marrow failure, and …
Renal phosphate transporters
E Lederer - Current opinion in nephrology and hypertension, 2014 - journals.lww.com
Increasing knowledge of structure function relationships for sodium phosphate
cotransporters, as well as greater appreciation for the complexity of their regulation and role …
cotransporters, as well as greater appreciation for the complexity of their regulation and role …
Phosphate uptake-independent signaling functions of the type III sodium-dependent phosphate transporter, PiT-1, in vascular smooth muscle cells
NW Chavkin, JJ Chia, MH Crouthamel… - Experimental cell …, 2015 - Elsevier
Vascular calcification (VC) is prevalent in chronic kidney disease and elevated serum
inorganic phosphate (Pi) is a recognized risk factor. The type III sodium-dependent …
inorganic phosphate (Pi) is a recognized risk factor. The type III sodium-dependent …
High phosphate actively induces cytotoxicity by rewiring pro‐survival and pro‐apoptotic signaling networks in HEK293 and HeLa cells
P He, O Mann‐Collura, J Fling, N Edara… - The FASEB …, 2021 - Wiley Online Library
Inorganic phosphate (Pi) is an essential nutrient for human health. Due to the changes in our
dietary pattern, dietary Pi overload engenders systemic phosphotoxicity, including excessive …
dietary pattern, dietary Pi overload engenders systemic phosphotoxicity, including excessive …
Disruption of the phosphate transporter Pit1 in hepatocytes improves glucose metabolism and insulin signaling by modulating the USP7/IRS1 interaction
A Forand, E Koumakis, A Rousseau, Y Sassier… - Cell reports, 2016 - cell.com
The liver plays a central role in whole-body lipid and glucose homeostasis. Increasing
dietary fat intake results in increased hepatic fat deposition, which is associated with a risk …
dietary fat intake results in increased hepatic fat deposition, which is associated with a risk …
Novel function of PiT1/SLC20A1 in LPS-related inflammation and wound healing
E Koumakis, J Millet-Botti, JE Benna, C Leroy… - Scientific reports, 2019 - nature.com
Abstract PiT1/SLC20A1 is an inorganic phosphate transporter with additional functions
including the regulation of TNFα-induced apoptosis, erythropoiesis, cell proliferation and …
including the regulation of TNFα-induced apoptosis, erythropoiesis, cell proliferation and …
PiT1/Slc20a1 is required for endoplasmic reticulum homeostasis, chondrocyte survival, and skeletal development
G Couasnay, N Bon, CS Devignes… - Journal of Bone and …, 2019 - academic.oup.com
During skeletal mineralization, the sodium‐phosphate co‐transporter PiT1Slc20a1 is
assumed to meet the phosphate requirements of bone‐forming cells, although evidence is …
assumed to meet the phosphate requirements of bone‐forming cells, although evidence is …
[HTML][HTML] Long noncoding RNA expression profiling in normal B-cell subsets and Hodgkin lymphoma reveals hodgkin and reed-sternberg cell–specific long noncoding …
MM Tayari, M Winkle, G Kortman, J Sietzema… - The American journal of …, 2016 - Elsevier
Hodgkin lymphoma (HL) is a malignancy of germinal center (GC) B-cell origin. To explore
the role of long noncoding RNAs (lncRNAs) in HL, we studied lncRNA expression patterns …
the role of long noncoding RNAs (lncRNAs) in HL, we studied lncRNA expression patterns …
PiT2 deficiency prevents increase of bone marrow adipose tissue during skeletal maturation but not in OVX-induced osteoporosis
G Frangi, M Guicheteau, F Jacquot, G Pyka… - Frontiers in …, 2022 - frontiersin.org
The common cellular origin between bone marrow adipocytes (BMAds) and osteoblasts
contributes to the intimate link between bone marrow adipose tissue (BMAT) and skeletal …
contributes to the intimate link between bone marrow adipose tissue (BMAT) and skeletal …