The fungal cell wall is located outside the plasma membrane and is the cell compartment
that mediates all the relationships of the cell with the environment. It protects the contents of …

Aspergillus fumigatus is an environmental filamentous fungus that can cause life-threatening
disease in immunocompromised individuals. The interactions between A. fumigatus and the …

Various diseases remain untreated due to lack of suitable therapeutic moiety or a suitable
drug delivery device, especially where toxicities and side effects are the primary reason for …

Few among the millions of fungal species fulfill four basic conditions necessary to infect
humans: high temperature tolerance, ability to invade the human host, lysis and absorption …

Fungi must meet four criteria to infect humans: growth at human body temperatures,
circumvention or penetration of surface barriers, lysis and absorption of tissue, and …

Aspergillus species are globally ubiquitous saprophytes found in a variety of ecological
niches. Almost 200 species of aspergilli have been identified, less than 20 of which are …

Here we identified a population of bone marrow neutrophils that constitutively expressed the
transcription factor RORγt and produced and responded to interleukin 17A (IL-17A (IL-17)) …

Inflammasomes are important sentinels of innate immune defence that are activated in
response to diverse stimuli, including pathogen-associated molecular patterns (PAMPs) …

Immunity to pathogens critically requires pattern-recognition receptors (PRRs) to trigger
intracellular signaling cascades that initiate and direct innate and adaptive immune …

Over the last decade, invasive fungal infections have emerged as a growing threat to human
health worldwide and novel treatment strategies are urgently needed. In this context …