Pancreatic cancer: a review of current treatment and novel therapies

HM Kolbeinsson, S Chandana, GP Wright… - Journal of Investigative …, 2023 - Taylor & Francis
Pancreatic cancer is one of the leading causes for cancer-related deaths in the United
States. Majority of patients present with unresectable or metastatic disease. For those that …

Primer on pulsed electrical field ablation: understanding the benefits and limitations

A Verma, SJ Asivatham, T Deneke… - Circulation …, 2021 - Am Heart Assoc
Pulsed electrical field (PEF) energy is a promising technique for catheter ablation of cardiac
arrhythmias. In this article, the key aspects that need to be considered for safe and effective …

Electroporation-based technologies for medicine: principles, applications, and challenges

ML Yarmush, A Golberg, G Serša… - Annual review of …, 2014 - annualreviews.org
When high-amplitude, short-duration pulsed electric fields are applied to cells and tissues,
the permeability of the cell membranes and tissue is increased. This increase in permeability …

A review of basic to clinical studies of irreversible electroporation therapy

C Jiang, RV Davalos, JC Bischof - IEEE Transactions on …, 2014 - ieeexplore.ieee.org
The use of irreversible electroporation (IRE) for cancer treatment has increased sharply over
the past decade. As a nonthermal therapy, IRE offers several potential benefits over other …

Irreversible electroporation: background, theory, and review of recent developments in clinical oncology

KN Aycock, RV Davalos - Bioelectricity, 2019 - liebertpub.com
Irreversible electroporation (IRE) has established a clinical niche as an alternative to thermal
ablation for the eradication of unresectable tumors, particularly those near critical vascular …

Investigation of the safety of irreversible electroporation in humans

KR Thomson, W Cheung, SJ Ellis, D Federman… - Journal of Vascular and …, 2011 - Elsevier
Purpose A single-center prospective nonrandomized cohort study was performed to
investigate the safety of irreversible electroporation (IRE) for tumor ablation in humans …

Safety and early efficacy of irreversible electroporation for hepatic tumors in proximity to vital structures

R Cannon, S Ellis, D Hayes… - Journal of surgical …, 2013 - Wiley Online Library
Introduction Irreversible electroporation (IRE) has shown promise for ablation of lesions in
proximity to vital structures in the preclinical setting. This study aims to evaluate the safety …

High-frequency irreversible electroporation (H-FIRE) for non-thermal ablation without muscle contraction

CB Arena, MB Sano, JH Rossmeisl, JL Caldwell… - Biomedical engineering …, 2011 - Springer
Background Therapeutic irreversible electroporation (IRE) is an emerging technology for the
non-thermal ablation of tumors. The technique involves delivering a series of unipolar …

Irreversible electroporation in medicine

B Rubinsky - Technology in cancer research & treatment, 2007 - journals.sagepub.com
This is a brief introduction to the emerging field of irreversible electroporation in medicine.
Certain electrical fields when applied across a cell can have as a sole effect the …

Acute and long-term effects of full-power electroporation ablation directly on the porcine esophagus

K Neven, R van Es, V van Driel… - Circulation …, 2017 - Am Heart Assoc
Background—Esophageal ulceration and fistula are complications of pulmonary vein
isolation using thermal energy sources. Irreversible electroporation is a novel, nonthermal …