Porcine epidemic diarrhea virus: An updated overview of virus epidemiology, virulence variation patterns and virus–host interactions
Y Zhang, Y Chen, J Zhou, X Wang, L Ma, J Li, L Yang… - Viruses, 2022 - mdpi.com
The porcine epidemic diarrhea virus (PEDV) is a member of the coronavirus family, causing
deadly watery diarrhea in newborn piglets. The global pandemic of PEDV, with significant …
deadly watery diarrhea in newborn piglets. The global pandemic of PEDV, with significant …
Improved vaccine against PRRSV: current progress and future perspective
Porcine reproductive and respiratory syndrome virus (PRRSV), one of the most
economically significant pathogens worldwide, has caused numerous outbreaks during the …
economically significant pathogens worldwide, has caused numerous outbreaks during the …
CD163 and pAPN double-knockout pigs are resistant to PRRSV and TGEV and exhibit decreased susceptibility to PDCoV while maintaining normal production …
K Xu, Y Zhou, Y Mu, Z Liu, S Hou, Y Xiong, L Fang… - Elife, 2020 - elifesciences.org
Porcine reproductive and respiratory syndrome virus (PRRSV) and transmissible
gastroenteritis virus (TGEV) are two highly infectious and lethal viruses causing major …
gastroenteritis virus (TGEV) are two highly infectious and lethal viruses causing major …
Macrophage-specific nanotechnology-driven CD163 overexpression in human macrophages results in an M2 phenotype under inflammatory conditions
M1 macrophages release proinflammatory factors during inflammation. They transit to an M2
phenotype and release anti-inflammatory factors to resolve inflammation. An imbalance in …
phenotype and release anti-inflammatory factors to resolve inflammation. An imbalance in …
Broad antagonism of coronaviruses nsp5 to evade the host antiviral responses by cleaving POLDIP3
Y Wu, M Li, J Tian, H Yan, Y Pan, H Shi, D Shi… - PLoS …, 2023 - journals.plos.org
Coronaviruses (CoVs) are a family of the largest RNA viruses that typically cause
respiratory, enteric, and hepatic diseases in animals and humans, imposing great threats to …
respiratory, enteric, and hepatic diseases in animals and humans, imposing great threats to …
TREM2 suppresses the proinflammatory response to facilitate PRRSV infection via PI3K/NF-κB signaling
Z Zhu, X Zhang, W Dong, X Wang, S He… - PLoS …, 2020 - journals.plos.org
Triggering receptor expressed on myeloid cells 2 (TREM2) serves as an anti-inflammatory
receptor, negatively regulating the innate immune response. TREM2 is mainly expressed on …
receptor, negatively regulating the innate immune response. TREM2 is mainly expressed on …
Tight junction protein occludin is a porcine epidemic diarrhea virus entry factor
X Luo, L Guo, J Zhang, Y Xu, W Gu, L Feng… - Journal of …, 2017 - Am Soc Microbiol
Porcine epidemic diarrhea virus (PEDV), the causative agent of porcine epidemic diarrhea,
has caused huge economic losses in pig-producing countries. Although PEDV was long …
has caused huge economic losses in pig-producing countries. Although PEDV was long …
Porcine epidemic diarrhea virus infection inhibits interferon signaling by targeted degradation of STAT1
L Guo, X Luo, R Li, Y Xu, J Zhang, J Ge, Z Bu… - Journal of …, 2016 - Am Soc Microbiol
Porcine epidemic diarrhea virus (PEDV) is a worldwide-distributed alphacoronavirus, but the
pathogenesis of PEDV infection is not fully characterized. During virus infection, type I …
pathogenesis of PEDV infection is not fully characterized. During virus infection, type I …
Innate immune evasion of porcine epidemic diarrhea virus through degradation of the FBXW7 protein via the ubiquitin-proteasome pathway
M Li, Y Wu, J Chen, H Shi, Z Ji, X Zhang, D Shi… - Journal of …, 2022 - Am Soc Microbiol
Porcine epidemic diarrhea virus (PEDV) causes a porcine disease associated with swine
epidemic diarrhea. Different antagonistic strategies have been identified, and the …
epidemic diarrhea. Different antagonistic strategies have been identified, and the …