Synergistic‐Catalysis‐Enabled Reaction of 2‐Indolymethanols with Oxonium Ylides for the Construction of 3‐Indolyl‐3‐Alkoxy Oxindole Frameworks

C Ma, JY Zhou, YZ Zhang, Y Jiao… - Chemistry–An Asian …, 2018 - Wiley Online Library
A synergistic‐catalysis‐enabled reaction of 2‐indolymethanols with oxonium ylides has
been established that makes use of a three‐component reaction between 3‐diazooxindoles …

Ag/P-stereogenic phosphine-catalyzed enantioselective 1, 3-dipolar cycloadditions: a method to optically active pyrrolidines

M Zhi, Z Gan, R Ma, H Cui, EQ Li, Z Duan… - Organic letters, 2019 - ACS Publications
A Ag/P-stereogenic phosphine-complex-catalyzed 1, 3-dipolar cycloaddition of azomethine
ylides with electron-deficient olefins is reported. In this reaction, highly functionalized …

Employing Arynes for the Generation of Aryl Anion Equivalents and Subsequent Reaction with Aldehydes

RN Gaykar, A Bhunia, AT Biju - The Journal of Organic Chemistry, 2018 - ACS Publications
Arynes are highly reactive intermediates, which are utilized for the electrophilic arylation of
various X–H bonds (X= O, N, S etc.). Herein, a new synthetic strategy is demonstrated …

Regio-and diastereoselective construction of a new set of functionalized pyrrolidine, spiropyrrolidine and spiropyrrolizidine scaffolds appended with aryl-and …

V Rajkumar, SA Babu, R Padmavathi - Tetrahedron, 2016 - Elsevier
Highly regio-and diastereoselective syntheses of a new set of functionalized pyrrolidines,
spiro-pyrrolidine/pyrrolizidine oxindoles, spiroacenaphthylenolyl-pyrrolidines/pyrrolizidines …

Pd‐Catalyzed Diastereoselective Intramolecular Amide α‐C−H Arylation in Sterically Hindered Monospirooxindole Motifs

D Shukla, SA Babu - Advanced Synthesis & Catalysis, 2019 - Wiley Online Library
This paper reveals the diastereoselective Pd‐catalyzed intramolecular α‐C (sp3)− H
arylation in amides. The intermolecular and intramolecular α‐arylation of tertiary C (sp3)− H …

Molecular diversity of the acid promoted domino reaction of 3-hydroxy-3-(indol-3-yl) indolin-2-ones and cyclic mercapto-substituted β-enamino esters

LN Pan, Q Wang, J Sun, QS Sun, CG Yan - New Journal of Chemistry, 2021 - pubs.rsc.org
The acetic acid promoted reaction of 3-hydroxy-3-(indol-3-yl) indolin-2-ones and mercapto-
substituted β-enamino esters showed very interesting molecular diversity. The reaction in …

Catalyst-Assisted Selective Vinylation and Methylallylation of a Quaternary Carbon Center Using tert-Butyl Acetate

N Mohanta, PP Samal, AM Pandey… - The Journal of …, 2023 - ACS Publications
The In (OTf) 3-catalyzed α-vinylation of various hydroxy-functionalized quaternary carbon
centers using in situ generated isobutylene from tert-butyl acetate is presented as a novel …

Rapid Construction of Complex 2-Pyrrolines through Lewis Acid-Catalyzed, Sequential Three-Component Reactions via in Situ-Generated 1-Azaallyl Cations

M Schlegel, C Schneider - Organic letters, 2018 - ACS Publications
The first Sc (OTf) 3-catalyzed dehydration of 2-hydroxy oxime ethers to generate benzylic
stabilized 1-azaallyl cations, which are captured by 1, 3-carbonyls, is described. A …

Lewis‐Acid‐Catalysed Reaction of 3‐Hydroxy‐2‐oxindoles with Terminal Alkynes: Synthetic Approaches to the Pyrroloindoline Alkaloids

LK Kinthada, KN Babu, D Padhi… - European Journal of …, 2017 - Wiley Online Library
Lewis‐acid‐catalysed reaction of 3‐hydroxy‐2‐oxindoles with a variety of terminal alkynes
has been developed. The key step involves alkylation of 3‐aryl (or) 3‐alkyl, 3 …

Efficient synthesis of highly functionalized indole and phenol containing 3, 3′-disubstituted oxindoles and chromene fused spirooxindoles

N Kumarswamyreddy, K Lokesh, V Kesavan - Tetrahedron Letters, 2018 - Elsevier
Alkynyl-3-OBoc oxindoles underwent Cu (II) mediated Friedel-Crafts alkylation with indoles
and phenols to yield of structurally diverse 3-alkynyl-3-indole/phenol-oxindole derivatives …