Estimating error rates for single molecule protein sequencing experiments
MB Smith, K VanderVelden, T Blom… - PLOS Computational …, 2024 - journals.plos.org
The practical application of new single molecule protein sequencing (SMPS) technologies
requires accurate estimates of their associated sequencing error rates. Here, we describe …
requires accurate estimates of their associated sequencing error rates. Here, we describe …
[HTML][HTML] Robust and scalable single-molecule protein sequencing with fluorosequencing
The need to accurately survey proteins and their modifications with ever higher sensitivities,
particularly in clinical settings with limited samples, is spurring development of new single …
particularly in clinical settings with limited samples, is spurring development of new single …
Amino acid sequence assignment from single molecule peptide sequencing data using a two-stage classifier
MB Smith, ZB Simpson… - PLOS Computational …, 2023 - journals.plos.org
We present a machine learning-based interpretive framework (whatprot) for analyzing single
molecule protein sequencing data produced by fluorosequencing, a recently developed …
molecule protein sequencing data produced by fluorosequencing, a recently developed …