Unraveling the roles of miRNAs in regulating epithelial-to-mesenchymal transition (EMT) in osteosarcoma

ZX Chong, SK Yeap, WY Ho - Pharmacological Research, 2021 - Elsevier
Osteosarcoma is one of the most prevalent primary bone tumors with a high metastatic and
recurrence rate with poor prognosis. MiRNAs are short and non-coding RNAs that could …

The role of miR-200 family in the regulation of hallmarks of cancer

K Klicka, TM Grzywa, A Mielniczuk, A Klinke… - Frontiers in …, 2022 - frontiersin.org
MiRNAs are short non-coding RNAs that regulate gene expression post-transcriptionally
contributing to the development of different diseases including cancer. The miR-200 family …

Hypoxic effects on matrix metalloproteinases' expression in the tumor microenvironment and therapeutic perspectives

G Gonzalez-Avila, B Sommer, E Flores-Soto… - International Journal of …, 2023 - mdpi.com
The tumor microenvironment (TME) is characterized by an acidic pH and low oxygen
concentrations. Hypoxia induces neoplastic cell evasion of the immune surveillance, rapid …

MiR-200c-3p contrasts PD-L1 induction by combinatorial therapies and slows proliferation of epithelial ovarian cancer through downregulation of β-catenin and c-myc

E Anastasiadou, E Messina, T Sanavia, L Mundo… - Cells, 2021 - mdpi.com
Conventional/targeted chemotherapies and ionizing radiation (IR) are being used both as
monotherapies and in combination for the treatment of epithelial ovarian cancer (EOC) …

microRNA-21 regulates stemness in pancreatic ductal adenocarcinoma cells

M Mortoglou, F Miralles, ED Arisan, A Dart… - International Journal of …, 2022 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) is the most common and aggressive type of
pancreatic cancer (PCa) with a low survival rate. microRNAs (miRs) are endogenous, non …

The Role of miRNAs in the Development, Proliferation, and Progression of Endometrial Cancer

A Bogaczyk, I Zawlik, T Zuzak, M Kluz… - International Journal of …, 2023 - mdpi.com
Endometrial cancer is one of the most common cancers in developing and developed
countries. Although the detection of this cancer is high at the early stages, there is still a lack …

miRNA-guided reprogramming of glucose and glutamine metabolism and its impact on cell adhesion/migration during solid tumor progression

L Quirico, F Orso, S Cucinelli, M Paradzik… - Cellular and molecular …, 2022 - Springer
MicroRNAs (miRNAs) are small, non-coding RNAs about 22 nucleotides in length that
regulate the expression of target genes post-transcriptionally, and are highly involved in …

A systematic review of microRNAs involved in Cervical cancer progression

RL Causin, AJA Freitas, CM Trovo Hidalgo Filho… - Cells, 2021 - mdpi.com
To obtain a better understanding on the role of microRNAs in the progression of cervical
cancer, a systematic review was performed to analyze cervical cancer microRNA studies …

The significant role of the microfilament system in tumors

X Jiang, Y Qin, L Kun, Y Zhou - Frontiers in oncology, 2021 - frontiersin.org
Actin is the structural protein of microfilaments, and it usually exists in two forms: monomer
and polymer. Among them, monomer actin is a spherical molecule composed of a …

Decreased expression of miR-23b is associated with poor survival of endometrial cancer patients

K Klicka, TM Grzywa, A Klinke, A Mielniczuk… - Scientific Reports, 2022 - nature.com
Endometrial cancer (EC) is one of the most common types of cancer of the female
reproductive system. EC is classified into two types (EC1 and EC2). MiRNAs are single …