Reactive oxygen species (ROS) are essential for cellular signaling and response to stress.
The level of ROS and the type of ROS determine the ability of cells to undergo cell death …

Alzheimer's disease (AD) is a prevalently found tauopathy characterized by memory loss
and cognitive insufficiency. AD is an age-related neurodegenerative disease with two major …

Emodin is an anthraquinone derivative found in the roots and bark of a variety of plants,
molds, and lichens. Emodin has been used as a traditional medication for more than 2000 …

Significance: Extensive research during the last quarter century has revealed that reactive
oxygen species (ROS) produced in the body, primarily by the mitochondria, play a major role …

Autophagy, a vital catabolic process that degrades cytoplasmic components within the
lysosome, is an essential cytoprotective response to pathologic stresses that occur during …

Alzheimer's disease (AD) is the most common type of dementia which characterized by a
progressive loss of memory and cognitive function due to degeneration of synapses and …

The accumulation of amyloid-β-containing neuritic plaques and intracellular tau protein
tangles are key histopathological hallmarks of Alzheimer's disease (AD). This type of …

Proteins are continuously affected by various intrinsic and extrinsic factors. Damaged
proteins influence several intracellular pathways and result in different disorders and …

Alzheimer's disease (AD) is accompanied by neural cell loss and memory deficit. Neural cell
death, occurring via apoptosis and autophagy, is widely observed in the AD brain in addition …

MicroRNAs are small non-coding nucleic acids that are responsible for regulating the gene
expression by binding to the coding region and 3'and 5'un-translated region of target …