Bacterial nucleoid-associated proteins, nucleoid structure and gene expression
SC Dillon, CJ Dorman - Nature Reviews Microbiology, 2010 - nature.com
Emerging models of the bacterial nucleoid show that nucleoid-associated proteins (NAPs)
and transcription contribute in combination to the dynamic nature of nucleoid structure …
and transcription contribute in combination to the dynamic nature of nucleoid structure …
Integrin structure, allostery, and bidirectional signaling
MA Arnaout, B Mahalingam… - Annu. Rev. Cell Dev. Biol., 2005 - annualreviews.org
Abstract αβ heterodimeric integrins mediate dynamic adhesive cell-cell and cell-extracellular
matrix (ECM) interactions in metazoa that are critical in growth and development …
matrix (ECM) interactions in metazoa that are critical in growth and development …
[HTML][HTML] Protein secondary structure prediction using deep convolutional neural fields
Protein secondary structure (SS) prediction is important for studying protein structure and
function. When only the sequence (profile) information is used as input feature, currently the …
function. When only the sequence (profile) information is used as input feature, currently the …
Atomic structure of the entire mammalian mitochondrial complex I
K Fiedorczuk, JA Letts, G Degliesposti, K Kaszuba… - Nature, 2016 - nature.com
Mitochondrial complex I (also known as NADH: ubiquinone oxidoreductase) contributes to
cellular energy production by transferring electrons from NADH to ubiquinone coupled to …
cellular energy production by transferring electrons from NADH to ubiquinone coupled to …
High speed BLASTN: an accelerated MegaBLAST search tool
Y Chen, W Ye, Y Zhang, Y Xu - Nucleic acids research, 2015 - academic.oup.com
Sequence alignment is a long standing problem in bioinformatics. The Basic Local
Alignment Search Tool (BLAST) is one of the most popular and fundamental alignment tools …
Alignment Search Tool (BLAST) is one of the most popular and fundamental alignment tools …
The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis
A Roczniak-Ferguson, CS Petit, F Froehlich, S Qian… - Science …, 2012 - science.org
Lysosomes are the major cellular site for clearance of defective organelles and digestion of
internalized material. Demand on lysosomal capacity can vary greatly, and lysosomal …
internalized material. Demand on lysosomal capacity can vary greatly, and lysosomal …
PredictProtein—an open resource for online prediction of protein structural and functional features
G Yachdav, E Kloppmann, L Kajan… - Nucleic acids …, 2014 - academic.oup.com
PredictProtein is a meta-service for sequence analysis that has been predicting structural
and functional features of proteins since 1992. Queried with a protein sequence it returns …
and functional features of proteins since 1992. Queried with a protein sequence it returns …
[HTML][HTML] The RIP1/RIP3 necrosome forms a functional amyloid signaling complex required for programmed necrosis
RIP1 and RIP3 kinases are central players in TNF-induced programmed necrosis. Here, we
report that the RIP homotypic interaction motifs (RHIMs) of RIP1 and RIP3 mediate the …
report that the RIP homotypic interaction motifs (RHIMs) of RIP1 and RIP3 mediate the …
I-TASSER: a unified platform for automated protein structure and function prediction
The iterative threading assembly refinement (I-TASSER) server is an integrated platform for
automated protein structure and function prediction based on the sequence-to-structure-to …
automated protein structure and function prediction based on the sequence-to-structure-to …
[HTML][HTML] IRGB10 liberates bacterial ligands for sensing by the AIM2 and caspase-11-NLRP3 inflammasomes
The inflammasome is an intracellular signaling complex, which on recognition of pathogens
and physiological aberration, drives activation of caspase-1, pyroptosis, and the release of …
and physiological aberration, drives activation of caspase-1, pyroptosis, and the release of …