Distinctions along the dorsal-ventral axis of medial prefrontal cortex (mPFC), between
anterior cingulate (AC), prelimbic (PL), and infralimbic (IL) sub-regions, have been proposed …

In recent years, there have been significant advances in our understanding of the positive
symptoms of schizophrenia, such as hallucinations and delusions. This progress has been …

Rationale Timing deficits are characteristic of developmental and neurodegenerative
disorders that are accompanied by cognitive impairment. A prominent theory of this interval …

Behaviours that have been rewarded intermittently persist for longer during periods of non-
reward than behaviours that have been rewarded continuously. This classic phenomenon is …

Hippocampal GABAA receptors containing the α5 subunit have been implicated in the
modulation of hippocampal-dependent learning, presumably via their tonic inhibitory …

The muscarinic acetylcholine receptor is an important modulator of medial prefrontal cortex
(mPFC) functions, such as the working memory required to bridge a trace interval in …

The anterior cingulate cortex (AC) component of the medial prefrontal cortex (mPFC) has
been implicated in attention and working memory as measured by trace conditioning. Since …

The nucleus accumbens (n. acc.) has been implicated in conditioning to both discrete and
contextual cues but its precise role is as yet controversial because conflicting patterns of …

Measures of anxiety in behavioural tests remain largely unclear even decades after their
establishment. Differences in the severity of anxiety measured by anxiety tests is an …

Previous studies have shown that low doses of ketamine, an N-methyl-D-aspartate receptor
antagonist, produce aberrantly strong internal representations of associatively activated but …