Abstract The coronavirus disease 2019 (COVID-19) pandemic has stimulated tremendous
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …

SARS-CoV-2 neutralizing antibodies play a critical role in COVID-19 prevention and
treatment but are challenged by viral evolution and the emergence of novel escape variants …

The development of neutralizing antibodies (nAbs) is an important strategy to tackle the
Omicron variant. Omicron N-terminal domain (NTD) mutations including A67V, G142D, and …

The highly mutated and transmissible Omicron (BA. 1) and its more contagious lineage BA.
2 have provoked serious concerns over their decreased sensitivity to the current COVID-19 …

Members of the Sarbecovirus subgenus of Coronaviridae have twice caused deadly threats
to humans. There is increasing concern about the rapid mutation of severe acute respiratory …

The pandemic of COVID-19 caused by SARS-CoV-2 continues to spread around the world.
Mutant strains of SARS-CoV-2 are constantly emerging. At present, Omicron variants have …

The understanding of any disease calls for studying specific biological structures called
epitopes. One important tool recently drawing attention and improving efficiency in both …

Bats carry genetically diverse severe acute respiratory syndrome-related coronaviruses
(SARSr-CoVs). Some of them utilize human angiotensin-converting enzyme 2 (hACE2) as a …

Abstract Coronavirus disease 2019 (COVID-19) was first reported three years ago, when a
group of individuals were infected with the original SARS-CoV-2 strain, based on which …

Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) neutralizing antibodies
are shown to be effective therapeutics for providing coronavirus disease 2019 (COVID‐19) …