Hemostasis encompasses a set of tightly regulated processes that govern blood clotting,
platelet activation, and vascular repair. Upon vascular injury, the hemostatic system initiates …

Uncontrolled haemorrhage is a major preventable cause of death in patients with traumatic
injury. Trauma-induced coagulopathy (TIC) describes abnormal coagulation processes that …

In recent years, the traditional view of the hemostatic system as being regulated by a
coagulation factor cascade coupled with platelet activation has been increasingly …

Neutrophils are well known for their role in infection and inflammatory disease and are first
responders at sites of infection or injury. Platelets have an established role in hemostasis …

Background The role of neutrophil extracellular traps (NETs) in procoagulant activity (PCA)
in stroke patients caused by thromboembolic occlusion of the internal carotid artery (ICA) …

Blood clot formation to stem bleeding from an injured blood vessel arises from a complex
series of cellular and biochemical events, which, when dysregulated, predispose to an …

Thrombo-inflammation describes the complex interplay between blood coagulation and
inflammation that plays a critical role in cardiovascular diseases. The third Maastricht …

Thromboinflammation or immunothrombosis is a concept that explains the existing link
between coagulation and inflammatory response present in many situations, such as sepsis …

Tissue factor (TF) plays a central role in haemostasis and thrombosis. Following vascular
damage, vessel wall TF initiates the extrinsic coagulation cascade. TF can also be exposed …

Background Colon cancer is invariably accompanied by altered coagulation activity;
however, the precise role of phosphatidylserine (PS) in the hypercoagulable state of colon …