Current state and future directions in the diagnosis of amyotrophic lateral sclerosis

M Vidovic, LH Müschen, S Brakemeier, G Machetanz… - Cells, 2023 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by
loss of upper and lower motor neurons, resulting in progressive weakness of all voluntary …

Artificial intelligence for biomarker discovery in Alzheimer's disease and dementia

LM Winchester, EL Harshfield, L Shi… - Alzheimer's & …, 2023 - Wiley Online Library
With the increase in large multimodal cohorts and high‐throughput technologies, the
potential for discovering novel biomarkers is no longer limited by data set size. Artificial …

Triclustering-based classification of longitudinal data for prognostic prediction: targeting relevant clinical endpoints in amyotrophic lateral sclerosis

DF Soares, R Henriques, M Gromicho… - Scientific Reports, 2023 - nature.com
This work proposes a new class of explainable prognostic models for longitudinal data
classification using triclusters. A new temporally constrained triclustering algorithm, termed …

Automatic prediction of amyotrophic lateral sclerosis progression using longitudinal speech transformer

L Wang, Y Gong, N Dawalatabad, M Vilela… - arXiv preprint arXiv …, 2024 - arxiv.org
Automatic prediction of amyotrophic lateral sclerosis (ALS) disease progression provides a
more efficient and objective alternative than manual approaches. We propose ALS …

Predictive modeling of ALS progression: an XGBoost approach using clinical features

R Gupta, M Bhandari, A Grover, T Al-Shehari, M Kadrie… - BioData Mining, 2024 - Springer
This research presents a predictive model aimed at estimating the progression of
Amyotrophic Lateral Sclerosis (ALS) based on clinical features collected from a dataset of 50 …

Harnessing deep learning into hidden mutations of neurological disorders for therapeutic challenges

S Yang, SH Kim, M Kang, JY Joo - Archives of Pharmacal Research, 2023 - Springer
The relevant study of transcriptome-wide variations and neurological disorders in the
evolved field of genomic data science is on the rise. Deep learning has been highlighted …

[HTML][HTML] Research and Application Progress of Radiomics in Neurodegenerative Diseases

J Feng, Y Huang, X Zhang, Q Yang, Y Guo, Y Xia… - Meta-Radiology, 2024 - Elsevier
Neurodegenerative diseases refer to degenerative diseases of the nervous system caused
by neuronal degeneration and apoptosis. Usually, the onset of the disease is insidious, and …

Examining ALS: reformed PCA and random forest for effective detection of ALS

A Alqahtani, S Alsubai, M Sha, AK Dutta - Journal of Big Data, 2024 - Springer
Abstract ALS (Amyotrophic Lateral Sclerosis) is a fatal neurodegenerative disease of the
human motor system. It is a group of progressive diseases that affects the nerve cells in the …

Implications of artificial intelligence algorithms in the diagnosis and treatment of motor neuron diseases—a review

D Lopez-Bernal, D Balderas, P Ponce, M Rojas… - Life, 2023 - mdpi.com
Motor neuron diseases (MNDs) are a group of chronic neurological disorders characterized
by the progressive failure of the motor system. Currently, these disorders do not have a …

Machine learning for ALSFRS-R score prediction: making sense of the sensor data

R Mehta, A Pramov, S Verma - arXiv preprint arXiv:2407.08003, 2024 - arxiv.org
Amyotrophic Lateral Sclerosis (ALS) is characterized as a rapidly progressive
neurodegenerative disease that presents individuals with limited treatment options in the …