Clinical classification of obesity and implications for metabolic dysfunction-associated fatty liver disease and treatment

Y Ding, Q Deng, M Yang, H Niu, Z Wang… - … Syndrome and Obesity, 2023 - Taylor & Francis
Obesity, and metabolic dysfunction-associated fatty liver disease (MAFLD) have reached
epidemic proportions globally. Obesity and MAFLD frequently coexist and act synergistically …

Tirzepatide as a novel effective and safe strategy for treating obesity: a systematic review and meta-analysis of randomized controlled trials

W Cai, R Zhang, Y Yao, Q Wu, J Zhang - Frontiers in public health, 2024 - frontiersin.org
Objective To systematically evaluate the efficacy and safety of a new hypoglycemic drug,
tirzepatide, for treating obesity based on indicators such as BMI, waist circumference, and …

Adults with metabolically healthy overweight or obesity present more brown adipose tissue and higher thermogenesis than their metabolically unhealthy counterparts

L Jurado-Fasoli, G Sanchez-Delgado, JMA Alcantara… - …, 2024 - thelancet.com
Background There is a subset of individuals with overweight/obesity characterized by a
lower risk of cardiometabolic complications, the so-called metabolically healthy …

Metabolically healthy obesity, transition from metabolic healthy to unhealthy status, and carotid atherosclerosis

Q Huang, Z Liu, M Wei, J Feng, Q Huang… - Diabetes/Metabolism …, 2024 - Wiley Online Library
Background Evidence of the effects of metabolically healthy obesity (MHO) on
atherosclerosis is limited; the transition effects of metabolic health and obesity phenotypes …

Biology and clinical use of glucagon-like-peptide-1 receptor agonists in vascular protection

K Yau, A Odutayo, S Dash, DZI Cherney - Canadian Journal of Cardiology, 2023 - Elsevier
Abstract Glucagon-like-peptide-1 receptor agonists (GLP1RA) are incretin agents initially
designed for the treatment of type 2 diabetes mellitus but due to pleiotropic actions are now …

[HTML][HTML] Body mass index and type 2 diabetes mellitus as metabolic determinants of immune checkpoint inhibitors response in melanoma

YJA Jan, CH Chiang, S Osataphan… - Journal for …, 2024 - pmc.ncbi.nlm.nih.gov
Abstract Background Immune checkpoint inhibitors (ICIs) have improved survival outcomes
in melanoma. Studies exploring the correlations between body mass index (BMI), type 2 …

Impact of coronary artery calcium on mortality and cardiovascular events in metabolic syndrome and diabetes among younger adults

S Masrouri, MD Shapiro, D Khalili… - European Journal of …, 2024 - academic.oup.com
Aims Whether coronary artery calcium (CAC) testing in younger individuals with metabolic
syndrome (MetS) and diabetes mellitus (DM) helps predict cardiovascular disease (CVD) …

Exploring the nexus: The place of kidney diseases within the cardiovascular-kidney-metabolic syndrome spectrum

M Kanbay, M Guldan, L Ozbek, S Copur… - European Journal of …, 2024 - Elsevier
Abstract Cardiovascular-kidney-metabolic (CKM) syndrome and chronic kidney disease
(CKD) are two significant comorbidities affecting a large proportion of the general population …

A novel risk factor for malignancy: albuminuria

M Kanbay, S Copur, ZY Yilmaz, C Tanriover… - European Journal of …, 2023 - Elsevier
Cancer is the second leading cause of death among the adult population following
cardiovascular diseases. Prevention and earlier diagnosis are among the cornerstones in …

Tirzepatide and potential use for metabolically healthy obesity

S Copur, C Tanriover, F Yavuz, KR Tuttle… - European journal of …, 2023 - Elsevier
Metabolically healthy obesity or metabolically healthy overweight (MHO) is best described
as being absent of any major metabolic disorder or cardiovascular diseases such as type 2 …