Summary Akkermansia muciniphila (A. muciniphila), an intestinal symbiont colonizing in the
mucosal layer, is considered to be a promising candidate as probiotics. A. muciniphila is …

The microbiota is composed of commensal bacteria and other microorganisms that live on
the epithelial barriers of the host. The commensal microbiota is important for the health and …

Background and Aims Dietary fat intake is associated with increased risk of colorectal
cancer (CRC). We examined the role of high-fat diet (HFD) in driving CRC through …

This study investigated the effects of water-soluble polysaccharide extracted from the
sporoderm-removed spores of Ganoderma lucidum (GLP) against AOM/DSS-induced …

Inflammatory bowel diseases (IBDs) develop as a result of complex interactions among
genes, innate immunity and environmental factors, which are related to the gut microbiota …

While gut microbiome and host gene regulation independently contribute to gastrointestinal
disorders, it is unclear how the two may interact to influence host pathophysiology. Here we …

Human diseases are increasingly linked with an altered or" dysbiotic" gut microbiota, but
whether such changes are causal, consequential, or bystanders to disease is, for the most …

Accumulating evidence indicates gut microbiota contributes to aging-related disorders.
However, the exact mechanism underlying gut dysbiosis-related pathophysiological …

Colorectal cancer is one of the so-called westernized diseases and the second leading
cause of cancer death worldwide. On the basis of global epidemiological and scientific …

The gastrointestinal tract harbors most of the microbiota associated with humans. In recent
years, there has been a surge of interest in assessing the relationships between the gut …