Biosynthesis and function of 7-deazaguanine derivatives in bacteria and phages

V de Crécy-Lagard, G Hutinet… - Microbiology and …, 2024 - Am Soc Microbiol
Deazaguanine modifications play multifaceted roles in the molecular biology of DNA and
tRNA, shaping diverse yet essential biological processes, including the nuanced fine-tuning …

Global analysis of aging-related protein structural changes uncovers enzyme-polymerization-based control of longevity

J Paukštytė, RML Cabezas, Y Feng, K Tong… - Molecular Cell, 2023 - cell.com
Aging is associated with progressive phenotypic changes. Virtually all cellular phenotypes
are produced by proteins, and their structural alterations can lead to age-related diseases …

RNA modifications as a common denominator between tRNA and mRNA

O Levi, YS Arava - Current Genetics, 2021 - Springer
Recent studies underscore RNA modifications as a novel mechanism to coordinate
expression and function of different genes. While modifications on the sugar or base …

Bacteriophage Infection of the Marine Bacterium Shewanella glacialimarina Induces Dynamic Changes in tRNA Modifications

M Lampi, P Gregorova, MS Qasim, NCV Ahlblad… - Microorganisms, 2023 - mdpi.com
Viruses are obligate intracellular parasites that, throughout evolution, have adapted
numerous strategies to control the translation machinery, including the modulation of post …

Permethylation of ribonucleosides provides enhanced mass spectrometry quantification of post-transcriptional RNA modifications

Y Xie, KA Janssen, A Scacchetti, EG Porter… - Analytical …, 2022 - ACS Publications
Chemical modifications of RNA are associated with fundamental biological processes such
as RNA splicing, export, translation, and degradation, as well as human disease states, such …

High-throughput profiling of RNA modifications by ultra-performance liquid chromatography coupled to complementary mass spectrometry: Methods, quality control …

G Huang, F Zhang, D Xie, Y Ma, P Wang, G Cao… - Talanta, 2023 - Elsevier
Although next-generation sequencing technology has been used to delineate RNA
modifications in recent years, the paucity of appropriate converting reactions or specific …

tRNA modification profiling reveals epitranscriptome regulatory networks in Pseudomonas aeruginosa

J Sun, J Wu, Y Yuan, L Fan, WLP Chua, YHS Ling… - …, 2024 - pmc.ncbi.nlm.nih.gov
Transfer RNA (tRNA) modifications have emerged as critical posttranscriptional regulators of
gene expression affecting diverse biological and disease processes. While there is …

Learning from the invaders: What viruses teach us about RNA-based regulation in microbes

LP Sarin - Microorganisms, 2022 - mdpi.com
Viruses feature an evolutionary shaped minimal genome that is obligately dependent on the
cellular transcription and translation machinery for propagation. To suppress host cell …

Cold-Active Shewanella glacialimarina TZS-4T nov. Features a Temperature-Dependent Fatty Acid Profile and Putative Sialic Acid Metabolism

MS Qasim, M Lampi, MMK Heinonen… - Frontiers in …, 2021 - frontiersin.org
Species of genus Shewanella are among the most frequently identified psychrotrophic
bacteria. Here, we have studied the cellular properties, growth dynamics, and stress …

Green chromatography techniques

S Goyal, R Sharma, J Singh, M Asadnia - Green Chemical Analysis and …, 2022 - Springer
It is crucial demand of recent times to make the industrial productions eco-friendly as much
as possible which not only promotes sustainable development but also lowers the financial …