Biosystem‐inspired engineering of nanozymes for biomedical applications

L Zhang, H Wang, X Qu - Advanced Materials, 2024 - Wiley Online Library
Nanozymes with intrinsic enzyme‐mimicking activities have shown great potential to
become surrogates of natural enzymes in many fields by virtue of their advantages of high …

Antioxidant and Prooxidant Nanozymes: From Cellular Redox Regulation to Next‐Generation Therapeutics

N Singh, GR Sherin, G Mugesh - Angewandte Chemie, 2023 - Wiley Online Library
Nanozymes, nanomaterials with enzyme‐mimicking activity, have attracted tremendous
interest in recent years owing to their ability to replace natural enzymes in various …

Cerium oxide nanoparticles with antioxidative neurorestoration for ischemic stroke

X Li, Z Han, T Wang, C Ma, H Li, H Lei, Y Yang… - Biomaterials, 2022 - Elsevier
Oxidative stress and mitochondrial damage are the main mechanisms of ischemia-
reperfusion injury in ischemic stroke. Herein, cerium oxide nanoparticles with powerful free …

Nanozyme‐enabled treatment of cardio‐and cerebrovascular diseases

Y Zhang, W Liu, X Wang, Y Liu, H Wei - Small, 2023 - Wiley Online Library
Cardio‐and cerebrovascular diseases are two major vascular‐related diseases that lead to
death worldwide. Reactive oxygen species (ROS) play a vital role in the occurrence and …

Translational selenium nanoparticles to attenuate allergic dermatitis through Nrf2-Keap1-driven activation of selenoproteins

B Xie, D Zeng, M Yang, Z Tang, L He, T Chen - ACS nano, 2023 - ACS Publications
Easy recurrence and strong treatment side effects significantly limit the clinical treatment of
allergic dermatitis. The human trace element selenium (Se) plays essential roles in redox …

Enzyme-mimetic antioxidant nanomaterials for ROS scavenging: Design, classification, and biological applications

S Zhou, H Cai, X He, Z Tang, S Lu - Coordination Chemistry Reviews, 2024 - Elsevier
Reactive oxygen species (ROS) perform vital functions in numerous life processes and
significantly affect physiological activities in different organ systems in the human body …

Cu2+‐Chelatable and ROS‐Scavenging MXenzyme as NIR‐II‐Triggered Blood–Brain Barrier‐Crossing Nanocatalyst against Alzheimer's Disease

C Du, W Feng, X Dai, J Wang, D Geng, X Li, Y Chen… - Small, 2022 - Wiley Online Library
Transition‐metal dyshomeostasis has been identified as a critical pathogenic factor for the
aggregates of amyloid‐beta (Aβ) peptide, which is associated with the onset and …

Traditional Chinese medicine active ingredients-based selenium nanoparticles regulate antioxidant selenoproteins for spinal cord injury treatment

S Rao, Y Lin, R Lin, J Liu, H Wang, W Hu… - Journal of …, 2022 - Springer
Abstract Background As Traditional Chinese Medicine (TCM) drugs, Huangqi and Danshen
are always applied in combination for spinal cord injury (SCI) treatment based on the …

A Bioinspired Manganese‐Organic Framework Ameliorates Ischemic Stroke through its Intrinsic Nanozyme Activity and Upregulating Endogenous Antioxidant …

J Wang, Y Wang, X Xiaohalati, Q Su, J Liu… - Advanced …, 2023 - Wiley Online Library
Following stroke, oxidative stress induced by reactive oxygen species (ROS) aggravates
neuronal damage and enlarges ischemic penumbra, which is devastating to stroke patients …

Manganese‐Based Nanozymes: Preparation, Catalytic Mechanisms, and Biomedical Applications

M Tang, Z Zhang, T Sun, B Li… - Advanced Healthcare …, 2022 - Wiley Online Library
Manganese (Mn) has attracted widespread attention due to its low‐cost, nontoxicity, and
valence‐rich transition. Various Mn‐based nanomaterials have sprung up and are …