Alzheimer's disease (AD) is a severe, chronic and progressive neurodegenerative disease
associated with memory and cognition impairment ultimately leading to death. It is the …

Polyphenols are an important class of phytochemicals, and several lines of evidence have
demonstrated their beneficial effects in the context of a number of pathologies including …

Alzheimer's disease (AD) is a devastative neurodegenerative disorder with complex
etiology. Apoptosis, a biological process that plays an essential role in normal physiology to …

The research of value-added applications for coffee silverskin (CSS) requires studies to
investigate potential bioactive compounds and biological activities in CSS extracts. In this …

Abstract Ethnopharmacological relevance Cornus officinalis (Cornaceae), known in Chinese
as “Shanzhuyu,” is a frequently used traditional Chinese medicine. It tastes sour and is …

Ursolic acid (UA) is a pentacyclic triterpene which is found in common herbs and medicinal
plants that are reputed for a variety of pharmacological effects. Both as an active principle of …

The brain of diabetics revealed deterioration in many regions, especially the hippocampus.
Hence, the present study aimed to evaluate the effects of gallic acid and p-coumaric acid …

Depression, a mood disorder, affects one in fifteen adults, has multiple risk factors and is
associated with complicated underlying pathological mechanisms. P-coumaric acid (p-CA) …

The aggregation of α-synuclein (α-syn) is considered the key pathogenic event in many
neurological disorders such as Parkinson's disease (PD), dementia with Lewy bodies and …

Neuroinflammatory responses induced by amyloid-beta peptide (Aβ) are important causes
in the pathogenesis of Alzheimer's disease (AD). Blockade of Aβ has emerged as a possible …