Current approaches and challenges for the metabolite profiling of complex natural extracts

JL Wolfender, G Marti, A Thomas, S Bertrand - Journal of Chromatography …, 2015 - Elsevier
Metabolite profiling is critical in many aspects of the life sciences, particularly natural product
research. Obtaining precise information on the chemical composition of complex natural …

Two-dimensional liquid chromatography: a state of the art tutorial

DR Stoll, PW Carr - Analytical chemistry, 2017 - ACS Publications
In this tutorial, we discuss the motivations for doing two-dimensional liquid chromatography
(2D-LC) and describe the commonly used implementations of the method. We review …

Recent advances in stationary phases and understanding of retention in hydrophilic interaction chromatography. A review

P Jandera, P Janás - Analytica Chimica Acta, 2017 - Elsevier
Hydrophilic interaction chromatography (HILIC) is a rapidly developing liquid
chromatography mode suitable for separation of strongly or moderately polar samples on …

Optimizing separations in online comprehensive two‐dimensional liquid chromatography

BWJ Pirok, AFG Gargano… - Journal of separation …, 2018 - Wiley Online Library
Online comprehensive two‐dimensional liquid chromatography has become an attractive
option for the analysis of complex nonvolatile samples found in various fields (eg …

Recent advances and trends in the liquid-chromatography–mass spectrometry analysis of flavonoids

A de Villiers, P Venter, H Pasch - Journal of Chromatography A, 2016 - Elsevier
Flavonoids have elicited significant attention as a result of their importance in plants, their
influence on the properties of natural-product derived commodities and especially as a …

Development of comprehensive online two-dimensional liquid chromatography/mass spectrometry using hydrophilic interaction and reversed-phase separations for …

DR Stoll, DC Harmes, GO Staples, OG Potter… - Analytical …, 2018 - ACS Publications
Monoclonal antibodies (mAb) and related molecules are being developed at a remarkable
pace as new therapeutics for the treatment of diseases ranging from cancer to inflammatory …

Comprehensive two-dimensional liquid chromatography as a powerful tool for the analysis of food and food products

F Cacciola, F Rigano, P Dugo, L Mondello - TrAC Trends in Analytical …, 2020 - Elsevier
Comprehensive two-dimensional liquid chromatography represents a valuable and powerful
tool for the analysis of very complex samples. This review article illustrates how the coupling …

Interactions of grape seed procyanidins with soy protein isolate: Contributing antioxidant and stability properties

YC Zou, CL Wu, CF Ma, S He, CS Brennan, Y Yuan - Lwt, 2019 - Elsevier
The interaction of grape seed procyanidins (GSP) with soy protein isolate (SPI) and the
characters of GSP/SPI complex were investigated. The experiment effects were determined …

Strategies to circumvent the solvent strength mismatch problem in online comprehensive two‐dimensional liquid chromatography

S Chapel, S Heinisch - Journal of Separation Science, 2022 - Wiley Online Library
On‐line comprehensive two‐dimensional liquid chromatography is a powerful technique for
the separation of highly complex samples. Due to the addition of the second dimension of …

Comprehensive two-dimensional hydrophilic interaction chromatography (HILIC)× reversed-phase liquid chromatography coupled to high-resolution mass …

CM Willemse, MA Stander, J Vestner… - Analytical …, 2015 - ACS Publications
Changes in anthocyanin chemistry represent some of the most important transformations
involved in red wine aging. However, accurate analysis of the derived pigments, as required …