Syncytiotrophoblast stress in preeclampsia: the convergence point for multiple pathways

CWG Redman, AC Staff, JM Roberts - American journal of obstetrics and …, 2022 - Elsevier
Preeclampsia evolves in 2 stages: a placental problem that generates signals to the mother
to cause a range of responses that comprise the second stage (preeclampsia syndrome) …

Subtypes of preeclampsia: recognition and determining clinical usefulness

JM Roberts, JW Rich-Edwards, TF McElrath… - …, 2021 - Am Heart Assoc
The concept that preeclampsia is a multisystemic syndrome is appreciated in both research
and clinical care. Our understanding of pathophysiology recognizes the role of inflammation …

Hypertensive disorders of pregnancy: ISSHP classification, diagnosis, and management recommendations for international practice

MA Brown, LA Magee, LC Kenny, SA Karumanchi… - …, 2018 - Am Heart Assoc
4. There are significant long-term cardiovascular risks for women with chronic hypertension
and those who have had gestational hypertension or preeclampsia. One initial …

Pre-eclampsia

BWJ Mol, CT Roberts, S Thangaratinam, LA Magee… - The Lancet, 2016 - thelancet.com
Summary Pre-eclampsia affects 3–5% of pregnancies and is traditionally diagnosed by the
combined presentation of high blood pressure and proteinuria. New definitions also include …

The complex aetiology of cerebral palsy

SJ Korzeniewski, J Slaughter, M Lenski… - Nature Reviews …, 2018 - nature.com
Cerebral palsy (CP) is the most prevalent, severe and costly motor disability of childhood.
Consequently, CP is a public health priority for prevention, but its aetiology has proved …

Preeclampsia and diabetes

TL Weissgerber, LM Mudd - Current diabetes reports, 2015 - Springer
Preeclampsia is diagnosed in women presenting with new onset hypertension accompanied
by proteinuria or other signs of severe organ dysfunction in the second half of pregnancy …

Hypertensive disorders of pregnancy: a systematic review of international clinical practice guidelines

TER Gillon, A Pels, P von Dadelszen, K MacDonell… - PloS one, 2014 - journals.plos.org
Background Clinical practice guidelines (CPGs) are developed to assist health care
providers in decision-making. We systematically reviewed existing CPGs on the HDPs …

Reveal, don't conceal: transforming data visualization to improve transparency

TL Weissgerber, SJ Winham, EP Heinzen… - Circulation, 2019 - Am Heart Assoc
Reports highlighting the problems with the standard practice of using bar graphs to show
continuous data have prompted many journals to adopt new visualization policies. These …

Pregnancy and long-term maternal cardiovascular health: progress through harmonization of research cohorts and biobanks

AC Staff, CWG Redman, D Williams, P Leeson… - …, 2016 - Am Heart Assoc
Background: Why We Need to Better Understand the Associations Between Pregnancy and
Future Cardiovascular Health In 2011, the American Heart Association added preeclampsia …

Differential activation of placental unfolded protein response pathways implies heterogeneity in causation of early‐and late‐onset pre‐eclampsia

HW Yung, D Atkinson, T Campion‐Smith… - The Journal of …, 2014 - Wiley Online Library
Based on gestational age at diagnosis and/or delivery, pre‐eclampsia (PE) is commonly
divided into early‐onset (< 34 weeks) and late‐onset (≥ 34 weeks) forms. Recently, the …