Diagnostic imaging of cardiac amyloidosis

A Martinez-Naharro, AJ Baksi, PN Hawkins… - Nature Reviews …, 2020 - nature.com
Systemic amyloidosis encompasses a debilitating, under-diagnosed but increasingly
recognized group of disorders characterized by the extracellular deposition of misfolded …

Cardiac amyloidosis: An underdiagnosed/underappreciated disease

AS Manolis, AA Manolis, TA Manolis… - European Journal of …, 2019 - Elsevier
Cardiac amyloidosis or amyloid cardiomyopathy (ACM), commonly resulting from
extracellular deposition of amyloid fibrils consisted of misfolded immunoglobulin light chain …

Low sensitivity of bone scintigraphy in detecting Phe64Leu mutation-related transthyretin cardiac amyloidosis

MB Musumeci, F Cappelli, D Russo, G Tini… - Cardiovascular …, 2020 - jacc.org
Objectives The aim of this study was to assess the diagnostic accuracy of bone scintigraphy
in a large multicenter cohort of patients with cardiac amyloidotic involvement and Phe64Leu …

Diagnosis and management of patients with left ventricular hypertrophy: Role of multimodality cardiac imaging. A scientific statement of the Heart Failure Association …

B Moura, A Aimo, A Al‐Mohammad… - European Journal of …, 2023 - Wiley Online Library
Left ventricular (LV) hypertrophy consists in an increased LV wall thickness. LV hypertrophy
can be either secondary, in response to pressure or volume overload, or primary, ie not …

[HTML][HTML] Cardiac amyloidosis: State-of-the-art review

S Bukhari - Journal of Geriatric Cardiology: JGC, 2023 - ncbi.nlm.nih.gov
Cardiac amyloidosis (CA) is caused by deposition of amyloid fibrils in the myocardium and
has two main subtypes, transthyretin cardiac amyloidosis (ATTR) and immunoglobulin light …

Assessment of cardiac amyloidosis with 99mTc-pyrophosphate (PYP) quantitative SPECT

C Ren, J Ren, Z Tian, Y Du, Z Hao, Z Zhang, W Fang… - EJNMMI physics, 2021 - Springer
Background 99m Tc-PYP scintigraphy provides differential diagnosis of ATTR
cardiomyopathy (ATTR-CM) from light chain cardiac amyloidosis and other myocardial …

Examining the sensitivity of 18F-NaF PET for the imaging of cardiac amyloidosis

P Martineau, V Finnerty, G Giraldeau, S Authier… - Journal of Nuclear …, 2021 - Elsevier
Background Conventional nuclear imaging with bone-seeking radiopharmaceuticals has
been shown to be a sensitive test for the detection of transthyretin cardiac amyloidosis …

Semi-quantitative indices of cardiac uptake in patients with suspected cardiac amyloidosis undergoing 99mTc-HMDP scintigraphy

C Gallini, F Tutino, R Martone, A Ciaccio… - Journal of Nuclear …, 2021 - Springer
Background 99mTc-HMDP scintigraphy has proved its efficacy in non-invasive diagnosis of
cardiac amyloidosis (CA) and is currently interpreted according to the Perugini qualitative …

Multimodal imaging and biomarkers in cardiac amyloidosis

MH Jung, S Chang, EJ Han, JC Youn - Diagnostics, 2022 - mdpi.com
Amyloidosis is a progressive infiltrative disease instigated by the extracellular deposition of
amyloid fibrils in various organs such as the heart, kidney, and peripheral nerves. Cardiac …

Radiopharmaceutical supply disruptions and the use of 99mTc-hydroxymethylene diphosphonate as an alternative to 99mTc-pyrophosphate for the diagnosis of …

EJ Miller, R Campisi, NR Shah, S McMahon… - Journal of Nuclear …, 2022 - Elsevier
There has been a transformation over the past decade in the diagnosis and management of
patients with amyloid transthyretin (ATTR) cardiac amyloidosis which has been driven by the …