Tuberculosis (TB) is a serious public health problem worldwide. Its situation is worsened by
the presence of multidrug resistant (MDR) strains of Mycobacterium tuberculosis, the …

Drug-resistant tuberculosis (DR-TB), including multi-and extensively drug-resistant TB, is
posing a significant challenge to effective treatment and TB control worldwide. New progress …

Tuberculosis (TB) remains one of the leading public health problems worldwide. Declared
as a global emergency in 1993 by the WHO, its control is hampered by the emergence of …

Mycobacterium tuberculosis is a serious human pathogen threat exhibiting complex
evolution of antimicrobial resistance (AMR). Accordingly, the many publicly available …

The emergence of multi-and extensively drug-resistant tuberculosis is a significant
impediment to the control of this disease because treatment becomes more complex and …

Tuberculosis (TB) is a formidable infectious disease that remains a major cause of death
worldwide today. Escalating application of genomic techniques has expedited the …

Fluoroquinolone resistance in Mycobacterium tuberculosis has become increasingly
important. A review of mutations in DNA gyrase, the fluoroquinolone target, is needed to …

Infectious diseases caused by clinically important Mycobacteria continue to be an important
public health problem worldwide primarily due to emergence of drug resistance crisis. In …

Modern chemotherapy has significantly improved patient outcomes against drug-sensitive
tuberculosis. However, the rapid emergence of drug-resistant tuberculosis, together with the …

We describe the design, development, analytical performance, and a limited clinical
evaluation of the 10-color Xpert MTB/XDR assay (CE-IVD only, not for sale in the United …