Vimentin at the core of wound healing

LS Coelho-Rato, S Parvanian, MK Modi… - Trends in Cell Biology, 2024 - cell.com
As a member of the large family of intermediate filaments (IFs), vimentin has emerged as a
highly dynamic and versatile cytoskeletal protein involved in many key processes of wound …

Impact of vimentin on regulation of cell signaling and matrix remodeling

Z Ostrowska-Podhorodecka, I Ding… - Frontiers in Cell and …, 2022 - frontiersin.org
Vimentin expression contributes to cellular mechanoprotection and is a widely recognized
marker of fibroblasts and of epithelial-mesenchymal transition. But it is not understood how …

Cell migration orchestrates migrasome formation by shaping retraction fibers

C Fan, X Shi, K Zhao, L Wang, K Shi, YJ Liu, H Li… - Journal of Cell …, 2022 - rupress.org
Migrasomes are recently discovered vesicle-like structures on retraction fibers of migrating
cells that have been linked with transfer of cellular contents, shedding of unwanted …

[HTML][HTML] Role of actin-binding proteins in the regulation of cellular mechanics

AV Vakhrusheva, AV Murashko, ES Trifonova… - European Journal of …, 2022 - Elsevier
The viscoelastic parameters of the cell can report on the cell state, cellular processes and
diseases. Cell mechanics strongly rely on the properties of the cytoskeleton, an important …

Cells in the polyaneuploid cancer cell (PACC) state have increased metastatic potential

MM Mallin, N Kim, MI Choudhury, SJ Lee… - Clinical & Experimental …, 2023 - Springer
Although metastasis is the leading cause of cancer deaths, it is quite rare at the cellular
level. Only a rare subset of cancer cells (~ 1 in 1.5 billion) can complete the entire metastatic …

Biocomposite materials based on poly (3-hydroxybutyrate) and chitosan: a review

Y Zhuikova, V Zhuikov, V Varlamov - Polymers, 2022 - mdpi.com
One of the important directions in the development of modern medical devices is the search
and creation of new materials, both synthetic and natural, which can be more effective in …

Desmin interacts directly with mitochondria

AA Dayal, NV Medvedeva, TM Nekrasova… - International Journal of …, 2020 - mdpi.com
Desmin intermediate filaments (IFs) play an important role in maintaining the structural and
functional integrity of muscle cells. They connect contractile myofibrils to plasma membrane …

Effects of titanium dioxide microparticles and nanoparticles on cytoskeletal organization, cell adhesion, migration, and proliferation in human gingival fibroblasts in the …

L Li, W Sun, J Yu, W Lei, H Zeng… - Journal of Periodontal …, 2022 - Wiley Online Library
Background and objective Titanium wear particles may participate in the etiology of peri‐
implantitis. However, the influence of titanium wear particles on biological behavior of …

Inactivating negative regulators of cortical branched actin enhances persistence of single cell migration

AI Fokin, A Boutillon, J James, L Courtois… - Journal of Cell …, 2024 - journals.biologists.com
ABSTRACT The Rac1–WAVE–Arp2/3 pathway pushes the plasma membrane by
polymerizing branched actin, thereby powering membrane protrusions that mediate cell …

Vimentin's side gig: Regulating cellular proteostasis in mammalian systems

CS Morrow, DL Moore - Cytoskeleton, 2020 - Wiley Online Library
Intermediate filaments (IFs) perform a diverse set of well‐known functions including
providing structural support for the cell and resistance to mechanical stress, yet recent …