Cone photoreceptor loss in light-damaged albino rats

MC Benthal, AS McKeown, TW Kraft - International Journal of Molecular …, 2022 - mdpi.com
We investigated the etiology of decreased cone-driven vision in a light damage (LD) model
of retinal degeneration. To induce slow, moderate degeneration, albino rats underwent low …

Scleral crosslinking using genipin can compromise retinal structure and function in tree shrews

M El Hamdaoui, AM Levy, AB Stuber, CA Girkin… - Experimental eye …, 2022 - Elsevier
Scleral crosslinking using genipin has been identified as a promising treatment approach for
myopia control. The efficacy of genipin to alter biomechanical properties of the sclera has …

Reverse translation of artificial intelligence in glaucoma: Connecting basic science with clinical applications

D Ma, LR Pasquale, MJA Girard, CKS Leung… - Frontiers in …, 2023 - frontiersin.org
Artificial intelligence (AI) has been approved for biomedical research in diverse areas from
bedside clinical studies to benchtop basic scientific research. For ophthalmic research, in …

Heterogenous thinning of peripapillary tissues occurs early during high myopia development in juvenile tree shrews

MT KhalafAllah, PA Fuchs, F Nugen… - Experimental Eye …, 2024 - Elsevier
Myopia is an independent risk factor for glaucoma, but the link between both conditions
remains unknown. Both conditions induce connective tissue remodeling at the optic nerve …

[HTML][HTML] Are Macula or Optic Nerve Head Structures Better at Diagnosing Glaucoma? An Answer Using Artificial Intelligence and Wide-Field Optical Coherence …

CYN Chiang, FA Braeu… - … Vision Science & …, 2024 - jov.arvojournals.org
Purpose: We wanted to develop a deep-learning algorithm to automatically segment optic
nerve head (ONH) and macula structures in three-dimensional (3D) wide-field optical …

[HTML][HTML] Longitudinal Changes of Bruch's Membrane Opening, Anterior Scleral Canal Opening, and Border Tissue in Experimental Juvenile High Myopia

MT KhalafAllah, PA Fuchs, F Nugen… - … & Visual Science, 2023 - tvst.arvojournals.org
Purpose: To investigate the relative positional changes between the Bruch's membrane
opening (BMO) and the anterior scleral canal opening (ASCO), and border tissue …

Comparing IOP-Induced Scleral Deformations in the Myopic and Myopic Glaucoma Spectrums

T Chuangsuwanich, TA Tun, FA Braeu… - … & Visual Science, 2024 - iovs.arvojournals.org
Purpose: To compare changes in macular curvature following acute IOP elevation across a
range of myopic conditions. Methods: We studied 328 eyes from 184 subjects, comprising …

Image segmentation of mouse eye in vivo with optical coherence tomography based on Bayesian classification

F Ma, S Wang, Y Guo, C Dai, J Meng - Biomedical Engineering …, 2024 - degruyter.com
Objectives Optical coherence tomography (OCT) is a new imaging technology that uses an
optical analog of ultrasound imaging for biological tissues. Image segmentation plays an …

Are Macula or Optic Nerve Head Structures better at Diagnosing Glaucoma? An Answer using AI and Wide-Field Optical Coherence Tomography

CYN Chiang, F Braeu, T Chuangsuwanich… - arXiv preprint arXiv …, 2022 - arxiv.org
Purpose:(1) To develop a deep learning algorithm to automatically segment structures of the
optic nerve head (ONH) and macula in 3D wide-field optical coherence tomography (OCT) …