Abstract Three lineages (BA. 1, BA. 2 and BA. 3) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern predominantly drove South Africa's …
JJ Lau, SMS Cheng, K Leung, CK Lee, A Hachim… - Nature medicine, 2023 - nature.com
Abstract The SARS-CoV-2 Omicron variant has demonstrated enhanced transmissibility and escape of vaccine-derived immunity. Although first-generation vaccines remain effective …
Background Little is known about the real-world effectiveness of oral antivirals against the SARS-CoV-2 omicron (B. 1.1. 529) variant. We aimed to assess the clinical effectiveness of …
Hong Kong SAR has adopted universal masking, social distancing, testing of all symptomatic and high-risk groups for isolation of confirmed cases in healthcare facilities …
Summary Background Hong Kong maintained low circulation of SARS-CoV-2 until a major community epidemic of the omicron (B. 1.1. 529) sublineage BA. 2 began in January, 2022 …
South Africa's fourth COVID-19 wave was driven predominantly by three lineages (BA. 1, BA. 2 and BA. 3) of the SARS-CoV-2 Omicron variant of concern. We have now identified two …
Summary Background Nirmatrelvir-ritonavir (Paxlovid) and ensitrelvir are 3-chymotrypsin- like cysteine protease (3CL pro) inhibitors which have been approved for the treatment of …
Background Viral rebound after nirmatrelvir–ritonavir treatment has implications for the clinical management and isolation of patients with COVID-19. We evaluated an unselected …
NNY Tsang, HC So, BJ Cowling, GM Leung… - The Lancet Infectious …, 2023 - thelancet.com
Background COVID-19 vaccines provide protection against symptomatic infection that might require medical attention and against severe outcomes; however, there is a paucity of …