The relative prevalence of the Omicron variant within SARS-CoV-2 infected cohorts in different countries: a systematic review

A Sarkar, S Omar, A Alshareef, K Fanous… - Human Vaccines & …, 2023 - Taylor & Francis
The Omicron variant of SARS-CoV-2 was detected in October 2021 and exhibited high
transmissibility, immune evasion, and reduced severity when compared to the earlier …

Emergence of SARS-CoV-2 omicron lineages BA. 4 and BA. 5 in South Africa

H Tegally, M Moir, J Everatt, M Giovanetti… - Nature medicine, 2022 - nature.com
Abstract Three lineages (BA. 1, BA. 2 and BA. 3) of the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) Omicron variant of concern predominantly drove South Africa's …

Real-world COVID-19 vaccine effectiveness against the Omicron BA. 2 variant in a SARS-CoV-2 infection-naive population

JJ Lau, SMS Cheng, K Leung, CK Lee, A Hachim… - Nature medicine, 2023 - nature.com
Abstract The SARS-CoV-2 Omicron variant has demonstrated enhanced transmissibility and
escape of vaccine-derived immunity. Although first-generation vaccines remain effective …

Real-world effectiveness of molnupiravir and nirmatrelvir plus ritonavir against mortality, hospitalisation, and in-hospital outcomes among community-dwelling …

CKH Wong, ICH Au, KTK Lau, EHY Lau, BJ Cowling… - The Lancet, 2022 - thelancet.com
Background Little is known about the real-world effectiveness of oral antivirals against the
SARS-CoV-2 omicron (B. 1.1. 529) variant. We aimed to assess the clinical effectiveness of …

Evolution and control of COVID-19 epidemic in Hong Kong

SC Wong, AKW Au, JYC Lo, PL Ho, IFN Hung, KKW To… - Viruses, 2022 - mdpi.com
Hong Kong SAR has adopted universal masking, social distancing, testing of all
symptomatic and high-risk groups for isolation of confirmed cases in healthcare facilities …

Vaccine effectiveness of one, two, and three doses of BNT162b2 and CoronaVac against COVID-19 in Hong Kong: a population-based observational study

ME McMenamin, J Nealon, Y Lin, JY Wong… - The Lancet Infectious …, 2022 - thelancet.com
Summary Background Hong Kong maintained low circulation of SARS-CoV-2 until a major
community epidemic of the omicron (B. 1.1. 529) sublineage BA. 2 began in January, 2022 …

Continued emergence and evolution of Omicron in South Africa: New BA. 4 and BA. 5 lineages

H Tegally, M Moir, J Everatt, M Giovanetti, C Scheepers… - MedRxiv, 2022 - medrxiv.org
South Africa's fourth COVID-19 wave was driven predominantly by three lineages (BA. 1, BA.
2 and BA. 3) of the SARS-CoV-2 Omicron variant of concern. We have now identified two …

Global prevalence of SARS-CoV-2 3CL protease mutations associated with nirmatrelvir or ensitrelvir resistance

JD Ip, AWH Chu, WM Chan, RCY Leung… - …, 2023 - thelancet.com
Summary Background Nirmatrelvir-ritonavir (Paxlovid) and ensitrelvir are 3-chymotrypsin-
like cysteine protease (3CL pro) inhibitors which have been approved for the treatment of …

Viral burden rebound in hospitalised patients with COVID-19 receiving oral antivirals in Hong Kong: a population-wide retrospective cohort study

CKH Wong, KTK Lau, ICH Au, EHY Lau… - The Lancet infectious …, 2023 - thelancet.com
Background Viral rebound after nirmatrelvir–ritonavir treatment has implications for the
clinical management and isolation of patients with COVID-19. We evaluated an unselected …

Effectiveness of BNT162b2 and CoronaVac COVID-19 vaccination against asymptomatic and symptomatic infection of SARS-CoV-2 omicron BA. 2 in Hong Kong: a …

NNY Tsang, HC So, BJ Cowling, GM Leung… - The Lancet Infectious …, 2023 - thelancet.com
Background COVID-19 vaccines provide protection against symptomatic infection that might
require medical attention and against severe outcomes; however, there is a paucity of …