Reward signals in the motor cortex: from biology to neurotechnology

G Derosiere, S Shokur, P Vassiliadis - Nature Communications, 2025 - nature.com
Over the past decade, research has shown that the primary motor cortex (M1), the brain's
main output for movement, also responds to rewards. These reward signals may shape …

Reinforcement-guided learning in frontal neocortex: emerging computational concepts

A Banerjee, RV Rikhye, A Marblestone - Current Opinion in Behavioral …, 2021 - Elsevier
The classical concepts of reinforcement learning in the mammalian brain focus on dopamine
release in the basal ganglia as the neural substrate of reward prediction errors, which drive …

Associations between sounds and actions in early auditory cortex of nonhuman primates

Y Huang, P Heil, M Brosch - Elife, 2019 - elifesciences.org
An individual may need to take different actions to the same stimulus in different situations to
achieve a given goal. The selection of the appropriate action hinges on the previously …

Task rule and choice are reflected by layer-specific processing in rodent auditory cortical microcircuits

MM Zempeltzi, M Kisse, MGK Brunk, C Glemser… - Communications …, 2020 - nature.com
The primary auditory cortex (A1) is an essential, integrative node that encodes the
behavioral relevance of acoustic stimuli, predictions, and auditory-guided decision-making …

Reward expectation modulates local field potentials, spiking activity and spike-field coherence in the primary motor cortex

J An, T Yadav, JP Hessburg, JT Francis - eneuro, 2019 - eneuro.org
Reward modulation (M1) could be exploited in developing an autonomously updating brain-
computer interface (BCI) based on a reinforcement learning (RL) architecture. For an …

Paradigm shift in sensorimotor control research and brain machine interface control: the influence of context on sensorimotor representations

Y Zhao, JP Hessburg, JN Asok Kumar… - Frontiers in …, 2018 - frontiersin.org
Neural activity in the primary motor cortex (M1) is known to correlate with movement related
variables including kinematics and dynamics. Our recent work, which we believe is part of a …

Near perfect neural critic from motor cortical activity toward an autonomously updating brain machine interface

J An, T Yadav, MB Ahmadi… - 2018 40th Annual …, 2018 - ieeexplore.ieee.org
We are developing an autonomously updating brain machine interface (BMI) utilizing
reinforcement learning principles. One aspect of this system is a neural critic that determines …

Noise-Correlation Is Modulated by Reward Expectation in the Primary Motor Cortex Bilaterally During Manual and Observational Tasks in Primates

B Moore, S Khang, JT Francis - Frontiers in Behavioral Neuroscience, 2020 - frontiersin.org
Reward modulation is represented in the motor cortex (M1) and could be used to implement
more accurate decoding models to improve brain-computer interfaces (BCIs; Zhao et al.,) …

Reward Modulates Local Field Potentials, Spiking Activity and Spike-Field Coherence in the Primary Motor Cortex

J An, T Yadav, JP Hessburg, JT Francis - bioRxiv, 2018 - biorxiv.org
Reward modulation of the primary motor cortex (M1) could be exploited in developing an
autonomously updating brain-machine interface (BMI) based on a reinforcement learning …

Primate Motor Cortical Activity Displays Hallmarks of a Temporal Difference Reinforcement Learning Process

VSA Tarigoppula, JS Choi, JP Hessburg… - 2023 11th …, 2023 - ieeexplore.ieee.org
Reinforcement learning (RL) models comprehensively describe neural dynamics of multiple
brain regions at several spatiotemporal scales during reinforcement-based learning. One of …