Mannose: a sweet option in the treatment of cancer and inflammation

F Nan, Y Sun, H Liang, J Zhou, X Ma… - Frontiers in …, 2022 - frontiersin.org
As a natural sugar, mannose is a type of hexose that is abundant in many different types of
fruits. Since mannose is rarely used for glycolysis in mammals, studies on the role of …

Biological function, regulatory mechanism, and clinical application of mannose in cancer

H Jin, X Liu, H Liu - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2023 - Elsevier
Studies examining the regulatory roles and clinical applications of monosaccharides other
than glucose in cancer have been neglected. Mannose, a common type of monosaccharide …

HPLC for simultaneous quantification of free mannose and glucose concentrations in serum: use in detection of ovarian cancer

Y Chen, Q Yao, L Zhang, P Zeng - Frontiers in Chemistry, 2023 - frontiersin.org
Background: Abnormal levels of monosaccharides in blood have been linked to
tumorigenesis. In this study, a novel high-performance liquid chromatography (HPLC) …

D-mannose reduces oxidative stress, inhibits inflammation, and increases treg cell proportions in mice with ulcerative colitis

Y Lu, Y Xiong, S Zhang, B Wang, Y Feng… - Frontiers in …, 2024 - frontiersin.org
Background Regulatory T (Treg) cells is required to dampen immune responses against
intestinal microbiota, which aid in a healthy body to promise that the resident gut microbiota …

Serum metabolomic profiling to reveal potential biomarkers for the diagnosis of fatty liver hemorrhagic syndrome in laying hens

L Guo, J Kuang, Y Zhuang, J Jiang, Y Shi… - Frontiers in …, 2021 - frontiersin.org
Fatty liver hemorrhage syndrome (FLHS), a nutritional and metabolic disease that frequently
occurs in laying hens, causes serious losses to the poultry industry. Nowadays, the …

Plasma mannose as a novel marker of myocardial infarction across different glycaemic states: a case control study

E Fortin, G Ferrannini, B Campi, L Mellbin… - Cardiovascular …, 2022 - Springer
Background Plasma mannose, an emerging novel biomarker of insulin resistance, is
associated with both diabetes mellitus and coronary atherosclerosis, but the relationship …

d-mannose blocks the interaction between keratinocytes and Th17 cells to alleviate psoriasis by inhibiting HIF-1α/CCL20 in mice

Q Jiang, B Wei, M You, X Zhou - International Immunopharmacology, 2023 - Elsevier
Psoriasis is an autoimmune chronic inflammatory skin disease with an unclear pathogenesis
that is difficult to cure, causing serious physical and mental burdens for patients. Previous …

The metabolomic signature of weight loss and remission in the Diabetes Remission Clinical Trial (DiRECT)

LJ Corbin, DA Hughes, CJ Bull, EE Vincent, ML Smith… - Diabetologia, 2024 - Springer
Aims/hypothesis High-throughput metabolomics technologies in a variety of study designs
have demonstrated a consistent metabolomic signature of overweight and type 2 diabetes …

Mannose as a biomarker of coronary artery disease: Angiographic evidence and clinical significance

E Ferrannini, N Marx, D Andreini, B Campi… - International journal of …, 2022 - Elsevier
Background High mannose has previously associated with insulin resistance and
cardiovascular disease (CVD). Our objective is to establish whether mannose is associated …

Untargeted metabolomics reveal signatures of a healthy lifestyle

W Pathmasiri, BR Rushing, S McRitchie… - Scientific Reports, 2024 - nature.com
This cross-sectional study investigated differences in the plasma metabolome in two groups
of adults that were of similar age but varied markedly in body composition and dietary and …