Personalized management of pheochromocytoma and paraganglioma

S Nölting, N Bechmann, D Taieb… - Endocrine …, 2022 - academic.oup.com
Pheochromocytomas/paragangliomas are characterized by a unique molecular landscape
that allows their assignment to clusters based on underlying genetic alterations. With around …

Genetics, diagnosis, management and future directions of research of phaeochromocytoma and paraganglioma: a position statement and consensus of the Working …

JWM Lenders, MN Kerstens, L Amar… - Journal of …, 2020 - journals.lww.com
Phaeochromocytoma and paraganglioma (PPGL) are chromaffin cell tumours that require
timely diagnosis because of their potentially serious cardiovascular and sometimes life …

European association of nuclear medicine practice guideline/society of nuclear medicine and molecular imaging procedure standard 2019 for radionuclide imaging of …

D Taïeb, RJ Hicks, E Hindié, BA Guillet… - European journal of …, 2019 - Springer
Purpose Diverse radionuclide imaging techniques are available for the diagnosis, staging,
and follow-up of phaeochromocytoma and paraganglioma (PPGL). Beyond their ability to …

Multidisciplinary practice guidelines for the diagnosis, genetic counseling and treatment of pheochromocytomas and paragangliomas

R García-Carbonero, F Matute Teresa… - Clinical and …, 2021 - Springer
Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors that
arise from chromaffin cells of the adrenal medulla and the sympathetic/parasympathetic …

An overview of 20 years of genetic studies in pheochromocytoma and paraganglioma

A Buffet, N Burnichon, J Favier… - Best practice & research …, 2020 - Elsevier
Paragangliomas and pheochromocytomas (PPGL) are rare neuroendocrine tumours
characterized by a strong genetic determinism. Over the past 20 years, evolution of PPGL …

Genomic and immune landscape Of metastatic pheochromocytoma and paraganglioma

B Calsina, E Piñeiro-Yáñez… - Nature …, 2023 - nature.com
The mechanisms triggering metastasis in pheochromocytoma/paraganglioma are unknown,
hindering therapeutic options for patients with metastatic tumors (mPPGL). Herein we show …

Targeted therapies in pheochromocytoma and paraganglioma

K Wang, J Crona, F Beuschlein… - The Journal of …, 2022 - academic.oup.com
Molecular targeted therapy plays an increasingly important role in the treatment of metastatic
pheochromocytomas and paragangliomas (PPGLs), which are rare tumors but remain …

Genetic bases of pheochromocytoma and paraganglioma

A Cascón, B Calsina, M Monteagudo… - Journal of …, 2023 - jme.bioscientifica.com
The genetics of pheochromocytoma and paraganglioma (PPGL) has become increasingly
complex over the last two decades. The list of genes involved in the development of these …

Genotype–phenotype correlations in pheochromocytoma and paraganglioma: a systematic review and individual patient meta-analysis

J Crona, A Lamarca, S Ghosal, S Welin… - Endocrine-related …, 2019 - erc.bioscientifica.com
Pheochromocytoma and paraganglioma (PPGL) can be divided into at least four molecular
subgroups. Whether such categorizations are independent factors for prognosis or …

Pheochromocytoma: a changing perspective and current concepts

A Kiriakopoulos, P Giannakis… - … in endocrinology and …, 2023 - journals.sagepub.com
This article aims to review current concepts in diagnosing and managing
pheochromocytoma and paraganglioma (PPGL). Personalized genetic testing is vital, as 40 …