The nasal cavity is an attractive route for both local and systemic drug delivery and holds
great potential for access to the brain via the olfactory region, an area where the blood–brain …

Background In nasal drug delivery system, nasal spray seems to be the most promising
delivery method for both local and systemic diseases therapy. Nasal deposition behavior is …

Nasal delivery offers many benefits over other conventional routes of delivery (eg oral or
intravenous administration). Benefits include, among others, a fast onset of action, non …

In vitro–in vivo correlation (IVIVC) allows prediction of in vivo drug deposition from a nasally
inhaled drug based on in vitro drug measurements. In vitro measurements include physical …

Background: High flow nasal cannula oxygen therapy (HFT) is increasingly used in intensive
and emergency care departments. Patients suffering from respiratory failure, who are likely …

Bioavailability assessment in the development phase of a drug product is vital to reveal the
disadvantageous properties of the substance and the possible technological interventions …

Nasal drug delivery has been utilized for locally acting diseases for decades. The nose is
also a portal to the systemic circulation and central nervous system (CNS). In the age of …

This review aims to cement three hot topics in drug delivery:(a) the pre-formulation of new
products intended for nose-to-brain delivery;(b) the development of nasal casts for studying …

This special report gives an insight in the rationale of utilizing the nasal cavity for drug
administration and the formulation as well as characterization of nasal preparations. As the …

The nose-to-brain delivery of ghrelin loaded in liposomes is a promising approach for the
management of cachexia. It could limit the plasmatic degradation of ghrelin and provide …